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CENPP and HAUS1
Data Source:
BioGRID
(two hybrid)
CENPP
HAUS1
Description
centromere protein P
HAUS augmin like complex subunit 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Spindle Pole
Centrosome
Cytosol
HAUS Complex
Mitotic Spindle Microtubule
Molecular Function
Protein Binding
Molecular_function
Protein Binding
Biological Process
CENP-A Containing Nucleosome Assembly
G2/M Transition Of Mitotic Cell Cycle
Centrosome Cycle
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Spindle Assembly
Cell Division
Ciliary Basal Body-plasma Membrane Docking
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Blood protein levels (
29875488
)
End-stage renal disease (
29885931
)
HDL cholesterol levels (
32203549
)
Height (
28552196
31562340
)
Malaria (
31844061
)
Pulse pressure (
30578418
)
Systolic blood pressure (
30224653
30578418
)
Triglyceride levels (
32203549
)
Urate levels (
31578528
)
Interacting Genes
27 interacting genes:
ATP6V0D2
BACH2
C2orf88
CCDC33
CCDC85B
CENPO
CEP44
GOLGA2
HAUS1
KIAA1328
KLC3
LMNA
MBD3
NHLH1
NTAQ1
PKNOX2
POLR3K
RNF126
RPIA
SERTAD3
STXBP1
SYCE1L
TEX11
TOX2
USHBP1
ZNF341
ZNF765
82 interacting genes:
AK8
ARFIP2
ATP6V1D
BFSP2
BLOC1S6
BORCS6
C3orf62
CAGE1
CBY2
CCDC136
CCDC57
CCHCR1
CDR2
CENPP
CEP170P1
CEP44
CEP55
CEP57L1
CEP63
CEP70
DCTN2
DMD
DTNBP1
FAM161B
FGFR1OP2
GOLGA2
HGS
HOOK2
IFIT3
IFT20
INCA1
KDM1A
KIFC3
KRT1
KRT15
KRT18
KRT19
KRT3
KRT31
KRT38
KRT40
KXD1
LDOC1
LURAP1
MAD1L1
MAGEA6
MCM10
MCM3
MED4
MED7
MIPOL1
MTUS2
NDC80
NECAB2
NINL
NUP54
NUP62
ODAD1
PDE4DIP
PIBF1
PKN1
POLR3C
SPAG5
SSC5D
STX11
SYCE1
SYCE3
TEAD4
TFIP11
TFPT
TRAF1
TRIM23
TRIM27
TRIM54
TRIM69
TSG101
TXN2
USHBP1
VPS37C
VPS52
WASHC3
ZNF471
Entrez ID
401541
115106
HPRD ID
17989
16385
Ensembl ID
ENSG00000188312
ENSG00000152240
Uniprot IDs
Q6IPU0
Q7Z672
Q96CS2
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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