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CENPP and CEP44
Data Source:
BioGRID
(two hybrid)
CENPP
CEP44
Description
centromere protein P
centrosomal protein 44
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Spindle Pole
Cytoplasm
Centrosome
Centriole
Midbody
Molecular Function
Protein Binding
Protein Binding
Microtubule Binding
Biological Process
CENP-A Containing Nucleosome Assembly
Centrosome Cycle
Centriole Replication
Centriole-centriole Cohesion
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Blood protein levels (
29875488
)
End-stage renal disease (
29885931
)
HDL cholesterol levels (
32203549
)
Height (
28552196
31562340
)
Malaria (
31844061
)
Pulse pressure (
30578418
)
Systolic blood pressure (
30224653
30578418
)
Triglyceride levels (
32203549
)
Urate levels (
31578528
)
Interacting Genes
27 interacting genes:
ATP6V0D2
BACH2
C2orf88
CCDC33
CCDC85B
CENPO
CEP44
GOLGA2
HAUS1
KIAA1328
KLC3
LMNA
MBD3
NHLH1
NTAQ1
PKNOX2
POLR3K
RNF126
RPIA
SERTAD3
STXBP1
SYCE1L
TEX11
TOX2
USHBP1
ZNF341
ZNF765
54 interacting genes:
ABI2
ABI3
ANKRD11
AQP1
BEND7
BFSP2
BLOC1S6
BYSL
CAB39
CBY2
CCDC116
CCDC146
CCDC185
CDC23
CENPP
CEP57L1
CHIC2
DCTN2
DHX57
DIP2A
ERAL1
FAM161A
FAM74A4
FXR2
GNG11
H2AP
HAUS1
ING5
KIAA0930
LINC02363
LMO1
LRRFIP1
MAPK9
MCRS1
MLLT6
MRFAP1L1
NAA10
PLEKHF2
POLR3C
POP5
PSMD3
RBM15
RECK
RNF8
SCNM1
TCEA2
TRIM41
TSGA10
TXLNA
ZFYVE26
ZNF250
ZNF417
ZNF587
ZNF688
Entrez ID
401541
80817
HPRD ID
17989
13885
Ensembl ID
ENSG00000188312
ENSG00000164118
Uniprot IDs
Q6IPU0
Q7Z672
Q9C0F1
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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