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STXBP1 and STX3
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology)
HPRD
(in vitro, in vivo)
STXBP1
STX3
Description
syntaxin binding protein 1
syntaxin 3
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Cytoskeleton
Plasma Membrane
Secretory Granule
Axon
Platelet Alpha Granule
Protein-containing Complex
Phagocytic Vesicle
Perinuclear Region Of Cytoplasm
Presynaptic Active Zone Membrane
Extracellular Exosome
Postsynapse
Glutamatergic Synapse
Vacuole
Plasma Membrane
Cell-cell Junction
Synaptic Vesicle
Endomembrane System
Integral Component Of Membrane
Apical Plasma Membrane
Lamellipodium
Dendrite
Growth Cone
SNARE Complex
Melanosome
Specific Granule
Azurophil Granule
Zymogen Granule Membrane
Neuron Projection
Presynaptic Active Zone Membrane
Extracellular Exosome
Schaffer Collateral - CA1 Synapse
Postsynapse
Glutamatergic Synapse
Molecular Function
SNARE Binding
RNA Binding
Protein Binding
Syntaxin-1 Binding
Protein Kinase Binding
Protein Domain Specific Binding
Syntaxin Binding
Identical Protein Binding
Phospholipase Binding
Protein N-terminus Binding
SNARE Binding
SNAP Receptor Activity
Protein Binding
Arachidonic Acid Binding
Biological Process
Platelet Degranulation
Developmental Process Involved In Reproduction
Intracellular Protein Transport
Vesicle Docking Involved In Exocytosis
Neurotransmitter Secretion
Neuromuscular Synaptic Transmission
Axon Target Recognition
Regulation Of Synaptic Vesicle Priming
Glutamate Secretion
Synaptic Vesicle Priming
Synaptic Vesicle Maturation
Vesicle-mediated Transport
Negative Regulation Of Protein-containing Complex Assembly
Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Negative Regulation Of Synaptic Transmission, GABAergic
Response To Estradiol
SNARE Complex Assembly
Regulation Of SNARE Complex Assembly
Positive Regulation Of Mast Cell Degranulation
Negative Regulation Of Neuron Apoptotic Process
Positive Regulation Of Calcium Ion-dependent Exocytosis
Protein Stabilization
Long-term Synaptic Depression
Platelet Aggregation
Cellular Response To Interferon-gamma
Protein Localization To Plasma Membrane
Presynaptic Dense Core Vesicle Exocytosis
Positive Regulation Of Vesicle Docking
Positive Regulation Of Glutamate Secretion, Neurotransmission
Regulation Of Acrosomal Vesicle Exocytosis
Intracellular Protein Transport
Exocytosis
Vesicle Fusion
Positive Regulation Of Cell Population Proliferation
Synaptic Vesicle Docking
Cytokine-mediated Signaling Pathway
Neuron Projection Development
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Positive Regulation Of Cell Adhesion
Vesicle Docking
Positive Regulation Of Chemotaxis
Long-term Synaptic Potentiation
Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane
Positive Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of Protein Localization To Cell Surface
Pathways
Regulation of insulin secretion
Neurexins and neuroligins
Other interleukin signaling
Drugs
Diseases
Early infantile epileptic encephalopathy; Ohtahara syndrome
GWAS
Body size at age 10 (
32376654
)
Whole brain grey matter density (
31530798
)
High chromosomal aberration frequency (chromosome type) (
31586183
)
Interacting Genes
34 interacting genes:
APBA1
APBA2
APP
BRME1
CDK5
CDK5R1
CENPP
DOC2A
DOC2B
HGS
MAPK1
MAPT
MEOX2
MTDH
MTNR1A
NEFH
NEFM
PLD1
PLD2
PRKCA
PRKCB
PRKCG
SPICE1
SPTBN1
SQSTM1
STX19
STX1A
STX1B
STX2
STX3
STX5
SYTL4
TRIM38
USO1
52 interacting genes:
AQP6
CD79A
COQ9
CPLX2
CPLX4
CREB3L1
CYB561
DNAJC5
EBAG9
ELOVL4
ERGIC3
EVI5
FAM209A
FXYD3
GPR152
GPX8
JAGN1
LMNA
MANBAL
MFSD14B
MGST3
MMGT1
MSMO1
MTIF3
NAPB
PGRMC2
REEP4
RMDN3
SCN3B
SLC35C2
SNAP23
SNAP25
SNAP29
STX1A
STX2
STX4
STX5
STXBP1
STXBP2
SYT1
SYT4
SYT7
TBC1D30
TMEM14B
TMPPE
TMX2
TRPC3
TXLNA
VAMP3
VAMP7
VAMP8
ZDHHC15
Entrez ID
6812
6809
HPRD ID
04235
15985
Ensembl ID
ENSG00000136854
ENSG00000166900
Uniprot IDs
P61764
Q13277
Q53YE2
PDB IDs
6L03
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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