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STXBP1 and STX19
Data Source:
BioGRID
(affinity chromatography technology, two hybrid)
STXBP1
STX19
Description
syntaxin binding protein 1
syntaxin 19
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Cytoskeleton
Plasma Membrane
Secretory Granule
Axon
Platelet Alpha Granule
Protein-containing Complex
Phagocytic Vesicle
Perinuclear Region Of Cytoplasm
Presynaptic Active Zone Membrane
Extracellular Exosome
Postsynapse
Glutamatergic Synapse
Plasma Membrane
Synaptic Vesicle
Endomembrane System
Integral Component Of Membrane
SNARE Complex
Presynaptic Active Zone Membrane
Molecular Function
SNARE Binding
RNA Binding
Protein Binding
Syntaxin-1 Binding
Protein Kinase Binding
Protein Domain Specific Binding
Syntaxin Binding
Identical Protein Binding
Phospholipase Binding
Protein N-terminus Binding
SNARE Binding
SNAP Receptor Activity
Protein Binding
Biological Process
Platelet Degranulation
Developmental Process Involved In Reproduction
Intracellular Protein Transport
Vesicle Docking Involved In Exocytosis
Neurotransmitter Secretion
Neuromuscular Synaptic Transmission
Axon Target Recognition
Regulation Of Synaptic Vesicle Priming
Glutamate Secretion
Synaptic Vesicle Priming
Synaptic Vesicle Maturation
Vesicle-mediated Transport
Negative Regulation Of Protein-containing Complex Assembly
Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Negative Regulation Of Synaptic Transmission, GABAergic
Response To Estradiol
SNARE Complex Assembly
Regulation Of SNARE Complex Assembly
Positive Regulation Of Mast Cell Degranulation
Negative Regulation Of Neuron Apoptotic Process
Positive Regulation Of Calcium Ion-dependent Exocytosis
Protein Stabilization
Long-term Synaptic Depression
Platelet Aggregation
Cellular Response To Interferon-gamma
Protein Localization To Plasma Membrane
Presynaptic Dense Core Vesicle Exocytosis
Positive Regulation Of Vesicle Docking
Positive Regulation Of Glutamate Secretion, Neurotransmission
Regulation Of Acrosomal Vesicle Exocytosis
Intracellular Protein Transport
Exocytosis
Vesicle Fusion
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Vesicle Docking
Pathways
Regulation of insulin secretion
Neurexins and neuroligins
Drugs
Diseases
Early infantile epileptic encephalopathy; Ohtahara syndrome
GWAS
Body size at age 10 (
32376654
)
Whole brain grey matter density (
31530798
)
Interacting Genes
34 interacting genes:
APBA1
APBA2
APP
BRME1
CDK5
CDK5R1
CENPP
DOC2A
DOC2B
HGS
MAPK1
MAPT
MEOX2
MTDH
MTNR1A
NEFH
NEFM
PLD1
PLD2
PRKCA
PRKCB
PRKCG
SPICE1
SPTBN1
SQSTM1
STX19
STX1A
STX1B
STX2
STX3
STX5
SYTL4
TRIM38
USO1
11 interacting genes:
ABI2
KDM1A
NAPB
PRKAB2
SCNM1
SNAP25
STXBP1
SUFU
SUV39H1
SYCE1
ZNF330
Entrez ID
6812
415117
HPRD ID
04235
14477
Ensembl ID
ENSG00000136854
ENSG00000178750
Uniprot IDs
P61764
Q8N4C7
PDB IDs
6L03
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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