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CENPP and NHLH1
Data Source:
BioGRID
(two hybrid, two hybrid)
CENPP
NHLH1
Description
centromere protein P
nescient helix-loop-helix 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Chromatin
Nucleus
Molecular Function
Protein Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Protein Dimerization Activity
Sequence-specific Double-stranded DNA Binding
Biological Process
CENP-A Containing Nucleosome Assembly
Regulation Of Transcription By RNA Polymerase II
Central Nervous System Development
Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Blood protein levels (
29875488
)
End-stage renal disease (
29885931
)
HDL cholesterol levels (
32203549
)
Height (
28552196
31562340
)
Malaria (
31844061
)
Pulse pressure (
30578418
)
Systolic blood pressure (
30224653
30578418
)
Triglyceride levels (
32203549
)
Urate levels (
31578528
)
Interacting Genes
27 interacting genes:
ATP6V0D2
BACH2
C2orf88
CCDC33
CCDC85B
CENPO
CEP44
GOLGA2
HAUS1
KIAA1328
KLC3
LMNA
MBD3
NHLH1
NTAQ1
PKNOX2
POLR3K
RNF126
RPIA
SERTAD3
STXBP1
SYCE1L
TEX11
TOX2
USHBP1
ZNF341
ZNF765
11 interacting genes:
CCT7
CENPP
CSRP3
HIVEP1
INO80E
LMO1
LMO2
LMO4
PIM1
PSME2
TCF3
Entrez ID
401541
4807
HPRD ID
17989
01212
Ensembl ID
ENSG00000188312
ENSG00000171786
Uniprot IDs
Q6IPU0
Q7Z672
Q02575
Q5T203
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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