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SIAH1 and NTAQ1
Data Source:
BioGRID
(two hybrid)
SIAH1
NTAQ1
Description
siah E3 ubiquitin protein ligase 1
N-terminal glutamine amidase 1
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Early Endosome
Cytosol
Plasma Membrane
Beta-catenin Destruction Complex
Nucleus
Cytosol
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Protein C-terminus Binding
Zinc Ion Binding
Ubiquitin Conjugating Enzyme Binding
Identical Protein Binding
Ubiquitin Protein Ligase Activity
Protein Binding
Protein-N-terminal Asparagine Amidohydrolase Activity
Protein-N-terminal Glutamine Amidohydrolase Activity
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Apoptotic Process
Cell Cycle
Spermatogenesis
Nervous System Development
Axon Guidance
Anatomical Structure Morphogenesis
Protein Catabolic Process
Protein Destabilization
Positive Regulation Of Apoptotic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Metabolic Process
Neuron Apoptotic Process
Negative Regulation Of Netrin-activated Signaling Pathway
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Cellular Protein Modification Process
Pathways
Netrin-1 signaling
Amyloid fiber formation
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Height (
28552196
)
Mean corpuscular hemoglobin (
32888494
)
Waist circumference (
28552196
)
Interacting Genes
151 interacting genes:
AASDHPPT
AFF1
AFF4
AIMP2
APC
AQP1
ARMC9
ATN1
ATXN7
AXIN1
BAG1
BAG3
BAG4
BCL6
CACYBP
CAPG
CCDC198
CDC23
CDC34
CDK5R1
DAB1
DCC
DDX41
DNAJC15
DNALI1
EEF1D
EIF3J
ELL2
EXOC3-AS1
FAM90A1
FLI1
FZD9
GAPDH
GDPD5
GRM5
H4-16
HIF1AN
HIPK2
HIPK3
INHA
IQCN
KATNAL1
KCNJ10
KHDRBS3
KIAA0319L
KIAA1217
KIF1B
KIF22
KIFC3
KLF10
LACTB2
LANCL2
LMNA
M1AP
MAB21L1
MAP3K5
MAPK12
MAPKBP1
MAPRE3
MOB3C
MTIF3
MX1
NANOS2
NANOS3
NECTIN2
NELFA
NOL6
NTAQ1
NUMB
NUMBL
OPRM1
OTUB2
PARD6B
PEG10
PEG3
PFKM
PHC1
PHC2
PIAS2
PIAS3
PIMREG
PKD1
POU2AF1
PRPF31
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PTPMT1
PUF60
PYGB
QRICH1
RAB33A
RAB33B
RAD51AP1
RAD54L2
RAPH1
RBBP8
RPL27A
RPS19BP1
RXRB
SDCBP
SFMBT2
SH3RF1
SLC9A3R2
SNCAIP
SPATA4
SPATC1L
SYP
SYT7
TBC1D22B
TERF2
TFDP1
TMEM43
TNK2
TOLLIP
TP53BP2
TRIM23
TRIM27
TRIM7
TRIM8
TUBA1A
TUBA1B
TUBA3C
TUBA4A
TUBA8
TXN
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E3
UBE2I
UBE2K
UBE2L6
UBE2N
UBE2V2
UPP2
USP19
UXT
VAV1
ZBP1
ZCCHC10
ZCCHC13
ZFYVE21
ZMAT3
ZNF148
ZNF512B
ZNF671
ZYX
380 interacting genes:
AARD
ACD
ACOT13
ACTB
ACTG1
ACTN2
ACY1
ADAMTSL4
AGR2
AGR3
AIMP2
AKIRIN2
AMOT
AMOTL2
AMPD2
ANKRD11
ANKRD36B
AOC1
APIP
ARID4B
ARL6IP1
ASL
ATP6V1G1
BANF2
BCL2L2-PABPN1
BEND5
BIRC7
BLMH
BLOC1S6
BLZF1
BOLA2
BOLA2B
BORCS6
BPIFB3
BTBD1
BTBD2
BTBD6
C1orf50
CAMK2A
CAPN3
CARD9
CASP6
CAVIN4
CBFA2T2
CBS
CBY2
CCDC102B
CCDC115
CCDC152
CCDC184
CCDC197
CCHCR1
CCNB1IP1
CD22
CDA
CDCA8
CDK2AP1
CDKN2AIPNL
CDR2
CENPP
CEP170B
CEP55
CEP70
CEP85
CGGBP1
CHCHD3
CHMP4A
CMTM5
COG6
COIL
CRYAA
CRYAA2
CSNK2B
CT45A1
CTAG1A
CTAG1B
CTBP1
CTH
CUEDC1
CUTC
CYSRT1
DAB1
DCTPP1
DEUP1
DHPS
DNAL4
DNM2
DYNLT1
EDARADD
EGLN3
EIF2B1
EIF4G1
EMILIN3
ENOX2
EP400
EPN3
ETV6
EXOSC8
FAM136A
FAM72A
FAM72D
FKBP6
FTH1
FTL
GADD45GIP1
GAS7
GCSAML
GFAP
GMCL1
GMDS
GNG3
GNMT
GNPDA2
GOLGA2
GOLGA6L9
GPX7
GRAMD4
GSTA4
GSTO2
GTF2H2C
H2AP
HAUS8
HBQ1
HBZ
HEATR5A
HGD
HIGD1C
HMG20A
HOMER3
HOXB6
HPRT1
HSD17B14
HSF2BP
HSPE1
HUS1
IKZF3
IL16
IL31
INCA1
ISCA2
ITGB3BP
JAKMIP2
JUP
KASH5
KATNBL1
KCNH1
KCTD1
KCTD10
KCTD13
KCTD15
KCTD21
KCTD4
KCTD6
KCTD7
KCTD9
KEAP1
KIF21B
KLHL12
KLHL2
KLHL20
KRT27
KRT31
KRTAP10-5
KRTAP10-7
KRTAP19-2
KRTAP19-6
KRTAP3-1
KRTAP3-3
KRTAP4-2
KRTAP5-9
KRTAP6-1
KRTAP9-2
KRTAP9-4
KRTAP9-8
L3MBTL3
LCE1C
LCE1D
LCE1E
LCE1F
LCE2C
LCE5A
LDB2
LENG1
LGALS2
LGALS9B
LIN7B
LMNA
LMO1
LMO2
LMO3
LNX2
LONRF1
LRIF1
LRRC73
LSM12
LSM14B
LZTFL1
LZTS1
LZTS2
MAB21L3
MAD1L1
MAGEA11
MAGEA12
MAGEA2
MAGEA2B
MALSU1
MARCHF10
MATN4
MDFI
MED22
MIF
MIF4GD
MIOS
MIPOL1
MIS18A
MITD1
MOB2
MORN3
MPLKIP
MRFAP1L1
MRPL12
MTHFD2L
MTUS2
MVP
MXRA8
MYD88
N4BP3
NAB2
NADSYN1
NAGK
NCOA5
NDUFAB1
NECAB2
NME1
NPL
NR5A1
NT5C1A
NTAN1
NUDT14
NUDT16L1
NUDT21
OOEP
PAK5
PCBD1
PFDN5
PGPEP1
PIH1D2
PLA2G10
PLCD1
PLEKHB2
PLEKHJ1
PNMA1
PNMA2
PNMA5
POLR2J
POMC
PPCDC
PPM1K
PPP1R27
PRKAR1B
PRMT1
PRMT5
PRPS2
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PRR23B
PRTFDC1
PSMB5
PSME3
PTS
PYCR3
PYGM
RAB42
RABAC1
RASAL3
RBBP8
RBM20
RBM45
RBM48
RBPMS
RD3
REEP6
RHOQ
RILPL1
RNF138
RNF4
ROPN1
RPIA
RUSC1
S100A11
SAP18
SARS2
SAT1
SCARA5
SELENOV
SEPTIN14
SEPTIN3
SFN
SH3GLB2
SIAH1
SIKE1
SIVA1
SLAIN1
SLC15A2
SLPI
SMAP1
SMN1
SNAP29
SNRPD3
SPANXB1
SPATA32
SPDYE4
SPINDOC
SPRYD7
SSNA1
SSX2IP
STH
STMN2
STN1
STX11
SYCE1L
SYNGAP1
TAX1BP1
TBX15
TCL1A
TCP10L
TEKT1
TEPSIN
THAP1
THAP6
THAP7
THG1L
TICAM2
TIFA
TLE5
TMEM239
TNFAIP1
TNIP3
TNR
TOLLIP
TRAF1
TRAF3
TRAF5
TRIM23
TRIM27
TRIM32
TRIM5
TRIM54
TRIM69
TRIM73
TRIM9
TRIP13
TSC22D1
TSN
TSNAX
UBR1
UBR2
UFC1
UNKL
VAC14
VCP
VDR
VPS37C
VXN
XIAP
ZBED1
ZBTB8A
ZBTB8B
ZC2HC1C
ZCCHC17
ZNF165
ZNF341
ZNF436
ZNF511
ZNF618
ZSCAN16
ZSCAN32
Entrez ID
6477
55093
HPRD ID
03736
07653
Ensembl ID
ENSG00000196470
ENSG00000156795
Uniprot IDs
Q8IUQ4
A0A3B3ITD7
A0A3B3ITI2
E5RHC2
Q96HA8
PDB IDs
2A25
4C9Z
4CA1
4I7B
4I7C
4I7D
4X3G
5WZZ
3C9Q
4W79
6KGJ
Enriched GO Terms of Interacting Partners
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