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SIAH1 and PRR20D
Data Source:
BioGRID
(two hybrid)
SIAH1
PRR20D
Description
siah E3 ubiquitin protein ligase 1
proline rich 20D
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Early Endosome
Cytosol
Plasma Membrane
Beta-catenin Destruction Complex
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Protein C-terminus Binding
Zinc Ion Binding
Ubiquitin Conjugating Enzyme Binding
Identical Protein Binding
Ubiquitin Protein Ligase Activity
Protein Binding
Identical Protein Binding
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Apoptotic Process
Cell Cycle
Spermatogenesis
Nervous System Development
Axon Guidance
Anatomical Structure Morphogenesis
Protein Catabolic Process
Protein Destabilization
Positive Regulation Of Apoptotic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Metabolic Process
Neuron Apoptotic Process
Negative Regulation Of Netrin-activated Signaling Pathway
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Netrin-1 signaling
Amyloid fiber formation
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Height (
28552196
)
Mean corpuscular hemoglobin (
32888494
)
Waist circumference (
28552196
)
Interacting Genes
151 interacting genes:
AASDHPPT
AFF1
AFF4
AIMP2
APC
AQP1
ARMC9
ATN1
ATXN7
AXIN1
BAG1
BAG3
BAG4
BCL6
CACYBP
CAPG
CCDC198
CDC23
CDC34
CDK5R1
DAB1
DCC
DDX41
DNAJC15
DNALI1
EEF1D
EIF3J
ELL2
EXOC3-AS1
FAM90A1
FLI1
FZD9
GAPDH
GDPD5
GRM5
H4-16
HIF1AN
HIPK2
HIPK3
INHA
IQCN
KATNAL1
KCNJ10
KHDRBS3
KIAA0319L
KIAA1217
KIF1B
KIF22
KIFC3
KLF10
LACTB2
LANCL2
LMNA
M1AP
MAB21L1
MAP3K5
MAPK12
MAPKBP1
MAPRE3
MOB3C
MTIF3
MX1
NANOS2
NANOS3
NECTIN2
NELFA
NOL6
NTAQ1
NUMB
NUMBL
OPRM1
OTUB2
PARD6B
PEG10
PEG3
PFKM
PHC1
PHC2
PIAS2
PIAS3
PIMREG
PKD1
POU2AF1
PRPF31
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PTPMT1
PUF60
PYGB
QRICH1
RAB33A
RAB33B
RAD51AP1
RAD54L2
RAPH1
RBBP8
RPL27A
RPS19BP1
RXRB
SDCBP
SFMBT2
SH3RF1
SLC9A3R2
SNCAIP
SPATA4
SPATC1L
SYP
SYT7
TBC1D22B
TERF2
TFDP1
TMEM43
TNK2
TOLLIP
TP53BP2
TRIM23
TRIM27
TRIM7
TRIM8
TUBA1A
TUBA1B
TUBA3C
TUBA4A
TUBA8
TXN
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E3
UBE2I
UBE2K
UBE2L6
UBE2N
UBE2V2
UPP2
USP19
UXT
VAV1
ZBP1
ZCCHC10
ZCCHC13
ZFYVE21
ZMAT3
ZNF148
ZNF512B
ZNF671
ZYX
89 interacting genes:
ABI2
ANKHD1
ARID5A
ATXN1
BANP
BEND2
BHLHE40
BICRAL
C10orf55
C1orf94
C3orf36
CABP2
CCNK
CDC37
CELF4
DAZAP2
DMRT3
DVL3
EIF4ENIF1
ESRP1
FAM168A
FAM222B
FAM9A
FOXH1
FOXP3
GLIS2
GTF2A1
HIVEP1
HLX
HYPK
KRTAP19-1
KRTAP19-5
LASP1
MAGED1
MBNL3
NCK2
NFYC
NOTCH3
NTAQ1
OXER1
PATZ1
PHF1
PITX1
POGZ
POU2F1
POU6F2
PRR20A
PRR20B
PRR20C
PRR20E
PRR34
PRR35
PTTG2
RBM23
RBM42
RBPMS
RBPMS2
RHOXF2
RIPPLY1
RNF4
ROR2
SAMD11
SH3RF1
SIAH1
SMAP1
SNRPB
SNRPC
SP4
SRPK2
TBX3
TBX6
TCF7L2
TFG
THAP1
TIAL1
TLX3
TOLLIP
TPRX1
TRIM35
VAC14
VENTX
VEZF1
VPS37C
YPEL3
ZBTB32
ZC3H10
ZCCHC14
ZNF385C
ZNF683
Entrez ID
6477
729246
HPRD ID
03736
19670
Ensembl ID
ENSG00000196470
ENSG00000227151
Uniprot IDs
Q8IUQ4
P86478
P86479
P86480
P86481
P86496
PDB IDs
2A25
4C9Z
4CA1
4I7B
4I7C
4I7D
4X3G
5WZZ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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