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SIAH1 and KIFC3
Data Source:
BioGRID
(two hybrid)
SIAH1
KIFC3
Description
siah E3 ubiquitin protein ligase 1
kinesin family member C3
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Early Endosome
Cytosol
Plasma Membrane
Beta-catenin Destruction Complex
Golgi Apparatus
Centrosome
Kinesin Complex
Microtubule
Zonula Adherens
Cytoplasmic Vesicle Membrane
Extracellular Exosome
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Protein C-terminus Binding
Zinc Ion Binding
Ubiquitin Conjugating Enzyme Binding
Identical Protein Binding
Ubiquitin Protein Ligase Activity
Microtubule Motor Activity
Protein Binding
ATP Binding
Microtubule Binding
ATP-dependent Microtubule Motor Activity, Minus-end-directed
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Apoptotic Process
Cell Cycle
Spermatogenesis
Nervous System Development
Axon Guidance
Anatomical Structure Morphogenesis
Protein Catabolic Process
Protein Destabilization
Positive Regulation Of Apoptotic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Metabolic Process
Neuron Apoptotic Process
Negative Regulation Of Netrin-activated Signaling Pathway
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Microtubule-based Movement
Golgi Organization
Visual Perception
Zonula Adherens Maintenance
Epithelial Cell-cell Adhesion
Pathways
Netrin-1 signaling
Amyloid fiber formation
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Height (
28552196
)
Mean corpuscular hemoglobin (
32888494
)
Waist circumference (
28552196
)
Interacting Genes
151 interacting genes:
AASDHPPT
AFF1
AFF4
AIMP2
APC
AQP1
ARMC9
ATN1
ATXN7
AXIN1
BAG1
BAG3
BAG4
BCL6
CACYBP
CAPG
CCDC198
CDC23
CDC34
CDK5R1
DAB1
DCC
DDX41
DNAJC15
DNALI1
EEF1D
EIF3J
ELL2
EXOC3-AS1
FAM90A1
FLI1
FZD9
GAPDH
GDPD5
GRM5
H4-16
HIF1AN
HIPK2
HIPK3
INHA
IQCN
KATNAL1
KCNJ10
KHDRBS3
KIAA0319L
KIAA1217
KIF1B
KIF22
KIFC3
KLF10
LACTB2
LANCL2
LMNA
M1AP
MAB21L1
MAP3K5
MAPK12
MAPKBP1
MAPRE3
MOB3C
MTIF3
MX1
NANOS2
NANOS3
NECTIN2
NELFA
NOL6
NTAQ1
NUMB
NUMBL
OPRM1
OTUB2
PARD6B
PEG10
PEG3
PFKM
PHC1
PHC2
PIAS2
PIAS3
PIMREG
PKD1
POU2AF1
PRPF31
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PTPMT1
PUF60
PYGB
QRICH1
RAB33A
RAB33B
RAD51AP1
RAD54L2
RAPH1
RBBP8
RPL27A
RPS19BP1
RXRB
SDCBP
SFMBT2
SH3RF1
SLC9A3R2
SNCAIP
SPATA4
SPATC1L
SYP
SYT7
TBC1D22B
TERF2
TFDP1
TMEM43
TNK2
TOLLIP
TP53BP2
TRIM23
TRIM27
TRIM7
TRIM8
TUBA1A
TUBA1B
TUBA3C
TUBA4A
TUBA8
TXN
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E3
UBE2I
UBE2K
UBE2L6
UBE2N
UBE2V2
UPP2
USP19
UXT
VAV1
ZBP1
ZCCHC10
ZCCHC13
ZFYVE21
ZMAT3
ZNF148
ZNF512B
ZNF671
ZYX
209 interacting genes:
ABI2
ABI3
ANKRD23
ANXA13
APP
APPL2
ARNT2
ATF2
AXIN2
BARD1
BCL6
BEGAIN
BFSP1
BYSL
C1orf109
C2CD6
CARD9
CBFA2T2
CBX8
CBY2
CCDC102B
CCDC136
CCDC146
CCDC187
CCDC198
CCDC28A
CCDC33
CCHCR1
CCND3
CDC37
CDK18
CDKN1A
CDR2
CEP55
CEP57L1
CLIP4
COG3
COG7
CREB5
CWF19L2
CYTH4
DCTN2
DCX
DEUP1
DISC1
DTNBP1
EIF3D
ENKD1
ESRRG
EXOC5
EXOC7
EXOC8
FAM124A
FAM161A
FAM90A1
FANCL
FBXO7
FCHSD2
FEM1A
FLYWCH1
FOSL1
GADD45GIP1
GEM
GIGYF1
GMCL1
GOLGA1
GOLGA2
GORASP2
HAUS1
HMG20A
HOMEZ
HSBP1
HSF2BP
ICA1L
IGFN1
IHO1
IKZF3
IL16
IQUB
ITGB3BP
KANK2
KANSL1
KDM1A
KIAA0753
KRT14
KRT15
KRT16
KRT18
KRT19
KRT26
KRT3
KRT31
KRT32
KRT35
KRT38
KRT40
KRT5
KRT6A
KRT6B
KRT6C
KRT75
KRT76
KRTAP19-5
KRTAP19-6
LBX1
LENG1
LIN37
LNX1
LZTS1
LZTS2
MBD3L1
MCC
MCM7
MED4
MFAP1
MID2
MKRN3
MOS
MRFAP1
MTUS2
MYO15B
NAB2
NDC80
NDEL1
NEBL
NECAB2
NEDD4
NEDD4L
NEFL
NSMF
NUP62
PFDN6
PHC2
PIAS2
PIBF1
PIN1
PNMA5
PPP1R13B
PRDM6
PRKAA2
PRPF18
PRPF31
PRPH
PSMB1
RABIF
RAD51D
RAD54L2
RBM41
RSPH14
RUNX1T1
SCEL
SCNM1
SCOC
SHISA6
SIAH1
SMARCE1
SNAP29
SORBS3
SOX30
SOX5
SPATA2
SPATC1L
SSX2IP
STMN3
STX11
STX1A
SVIL
SYCE1
SYCE2
SYT6
SYTL4
TASOR2
TBC1D22B
TCEANC
TFIP11
TLE5
TNIP1
TNNI1
TPM3
TRAF2
TRIM14
TRIM23
TRIM27
TRIM41
TRIM54
TSG101
TSGA10IP
TSR2
USH1G
USP2
VIM
VPS52
WASF3
ZBED1
ZBTB16
ZBTB8A
ZGPAT
ZNF180
ZNF20
ZNF250
ZNF417
ZNF446
ZNF572
ZNF655
ZNF688
ZNF774
ZNF785
ZNF835
ZRANB1
Entrez ID
6477
3801
HPRD ID
03736
05171
Ensembl ID
ENSG00000196470
ENSG00000140859
Uniprot IDs
Q8IUQ4
B7Z5U4
B7Z808
B7Z896
F5H3M2
Q9BVG8
PDB IDs
2A25
4C9Z
4CA1
4I7B
4I7C
4I7D
4X3G
5WZZ
5WDE
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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