KIFC3 and EIF3D

Data Source:
BioGRID (two hybrid)

		KIFC3	EIF3D
Description		kinesin family member C3	eukaryotic translation initiation factor 3 subunit D
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GO Annotations	Cellular Component	Golgi Apparatus Centrosome Kinesin Complex Microtubule Zonula Adherens Cytoplasmic Vesicle Membrane Extracellular Exosome	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Minus-end-directed	RNA Binding Translation Initiation Factor Activity Protein Binding MRNA Cap Binding
	Biological Process	Microtubule-based Movement Golgi Organization Visual Perception Zonula Adherens Maintenance Epithelial Cell-cell Adhesion	Formation Of Cytoplasmic Translation Initiation Complex Cap-dependent Translational Initiation Translational Initiation Positive Regulation Of Translation IRES-dependent Viral Translational Initiation Viral Translational Termination-reinitiation Positive Regulation Of MRNA Binding
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS
Interacting Genes		209 interacting genes: ABI2 ABI3 ANKRD23 ANXA13 APP APPL2 ARNT2 ATF2 AXIN2 BARD1 BCL6 BEGAIN BFSP1 BYSL C1orf109 C2CD6 CARD9 CBFA2T2 CBX8 CBY2 CCDC102B CCDC136 CCDC146 CCDC187 CCDC198 CCDC28A CCDC33 CCHCR1 CCND3 CDC37 CDK18 CDKN1A CDR2 CEP55 CEP57L1 CLIP4 COG3 COG7 CREB5 CWF19L2 CYTH4 DCTN2 DCX DEUP1 DISC1 DTNBP1 EIF3D ENKD1 ESRRG EXOC5 EXOC7 EXOC8 FAM124A FAM161A FAM90A1 FANCL FBXO7 FCHSD2 FEM1A FLYWCH1 FOSL1 GADD45GIP1 GEM GIGYF1 GMCL1 GOLGA1 GOLGA2 GORASP2 HAUS1 HMG20A HOMEZ HSBP1 HSF2BP ICA1L IGFN1 IHO1 IKZF3 IL16 IQUB ITGB3BP KANK2 KANSL1 KDM1A KIAA0753 KRT14 KRT15 KRT16 KRT18 KRT19 KRT26 KRT3 KRT31 KRT32 KRT35 KRT38 KRT40 KRT5 KRT6A KRT6B KRT6C KRT75 KRT76 KRTAP19-5 KRTAP19-6 LBX1 LENG1 LIN37 LNX1 LZTS1 LZTS2 MBD3L1 MCC MCM7 MED4 MFAP1 MID2 MKRN3 MOS MRFAP1 MTUS2 MYO15B NAB2 NDC80 NDEL1 NEBL NECAB2 NEDD4 NEDD4L NEFL NSMF NUP62 PFDN6 PHC2 PIAS2 PIBF1 PIN1 PNMA5 PPP1R13B PRDM6 PRKAA2 PRPF18 PRPF31 PRPH PSMB1 RABIF RAD51D RAD54L2 RBM41 RSPH14 RUNX1T1 SCEL SCNM1 SCOC SHISA6 SIAH1 SMARCE1 SNAP29 SORBS3 SOX30 SOX5 SPATA2 SPATC1L SSX2IP STMN3 STX11 STX1A SVIL SYCE1 SYCE2 SYT6 SYTL4 TASOR2 TBC1D22B TCEANC TFIP11 TLE5 TNIP1 TNNI1 TPM3 TRAF2 TRIM14 TRIM23 TRIM27 TRIM41 TRIM54 TSG101 TSGA10IP TSR2 USH1G USP2 VIM VPS52 WASF3 ZBED1 ZBTB16 ZBTB8A ZGPAT ZNF180 ZNF20 ZNF250 ZNF417 ZNF446 ZNF572 ZNF655 ZNF688 ZNF774 ZNF785 ZNF835 ZRANB1	31 interacting genes: ANKRD28 BEND5 CCDC125 CCDC57 CDC42 CEP70 CREBBP DNAJB11 DVL3 EIF3G EIF3J EIF3L EIF5 ERCC6 GOLGA6L9 HOMER3 HOOK2 HSF2BP KIFC3 LZTS2 MORN3 MTUS2 PHLDA1 PICK1 POLR2G REL SAT1 TFIP11 TRIM23 TRIM27 ZRANB1
Entrez ID		3801	8664
HPRD ID		05171	04888
Ensembl ID		ENSG00000140859	ENSG00000100353
Uniprot IDs		B7Z5U4 B7Z808 B7Z896 F5H3M2 Q9BVG8	O15371
PDB IDs		5WDE	6YBD 6YBS 6ZMW 6ZON 6ZP4 6ZVJ 7A09
Enriched GO Terms of Interacting Partners?
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