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SRSF3 and DUX4
Data Source:
BioGRID
(pull down)
SRSF3
DUX4
Description
serine and arginine rich splicing factor 3
double homeobox 4
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Nuclear Speck
Nucleus
Nucleoplasm
Nucleolus
Golgi Apparatus
Cytosol
Nuclear Membrane
Molecular Function
RNA Binding
Protein Binding
Phospholipase Binding
Sequence-specific MRNA Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
MRNA Splicing, Via Spliceosome
RNA Export From Nucleus
MRNA Export From Nucleus
MRNA 3'-end Processing
Regulation Of MRNA Splicing, Via Spliceosome
Cellular Response To Leukemia Inhibitory Factor
Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Multicellular Organism Development
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of G0 To G1 Transition
Pathways
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Mean corpuscular volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Vertical cup-disc ratio (adjusted for vertical disc diameter) (
31959993
)
Vertical cup-disc ratio (multi-trait analysis) (
31959993
)
Interacting Genes
39 interacting genes:
APP
CHD1
CIRBP
CLK1
CLK2
CLK3
CNNM3
DUX4
EXOSC6
GEMIN2
HNRNPK
IL7R
LNX1
NXF1
PCBP1
PCBP2
PCBP3
PCDHB14
PRPF31
RBM3
RBM7
RBMX
RBMY1A1
RNPS1
RPL9
SCAF11
SDCBP
SREK1
SRPK1
SRPK2
SRSF2
SRSF8
TRA2B
U2AF1
U2AF1L5
U2AF2
YWHAB
YWHAG
YWHAQ
124 interacting genes:
ACTG1
AP2A1
AP3D1
ARF1
ATP5F1C
C1QBP
CAND1
CAPN2
CAVIN1
CCT6A
CLTC
COPA
CSE1L
DDX21
DDX3X
DDX5
DES
DHX30
DHX36
DHX9
DYNC1H1
EEF2
EFTUD2
ENO1
EP300
EPRS1
FASN
FLNA
GAPDH
GARS1
HMGB1
HNRNPA1L2
HNRNPF
HNRNPH1
HNRNPK
HNRNPM
HNRNPU
HSPD1
IARS1
IGF2BP1
IGF2BP3
ILF3
IQGAP1
LDHA
MARS1
MCM7
MTHFD1
MYBBP1A
MYH10
MYH9
MYL6B
NCL
NPM1
PABPC1
PABPC4
PARP1
PFAS
PKM
PPP2R1A
PRKDC
PRPF8
RAN
RPL10
RPL10A
RPL12
RPL13
RPL15
RPL17
RPL18
RPL19
RPL21
RPL22
RPL23
RPL23A
RPL27A
RPL3
RPL30
RPL31
RPL35
RPL36
RPL4
RPL6
RPL7
RPL7A
RPL8
RPL9
RPN1
RPS10
RPS13
RPS14
RPS15
RPS15A
RPS16
RPS17
RPS18
RPS2
RPS20
RPS24
RPS25
RPS3
RPS3A
RPS4X
RPS6
RPS7
RPS8
RPS9
SF3B1
SHMT2
SLC25A3
SLC25A5
SLC25A6
SNRNP200
SRSF3
TCP1
TUBB
TUBB2A
TUBB3
TUBB6
VDAC1
VDAC2
VIM
XRCC5
XRCC6
YBX1
Entrez ID
6428
100288687
HPRD ID
04530
Ensembl ID
ENSG00000112081
ENSG00000260596
Uniprot IDs
B2R6F3
P84103
C3U3A0
Q9UBX2
PDB IDs
2I2Y
2I38
5Z2S
5Z2T
5Z6Z
5ZFW
5ZFY
5ZFZ
6A8R
6DFY
6E8C
6U81
6U82
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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