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UBQLN1 and MTNR1A
Data Source:
BioGRID
(two hybrid)
UBQLN1
MTNR1A
Description
ubiquilin 1
melatonin receptor 1A
Image
GO Annotations
Cellular Component
Proteasome Complex
Nucleoplasm
Cytoplasm
Autophagosome
Endoplasmic Reticulum
Cytosol
Plasma Membrane
Aggresome
Cytoplasmic Vesicle
Protein-containing Complex
Perinuclear Region Of Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Receptor Complex
Molecular Function
Protein Binding
Kinase Binding
Polyubiquitin Modification-dependent Protein Binding
Identical Protein Binding
G Protein-coupled Receptor Activity
Protein Binding
Melatonin Receptor Activity
Hormone Binding
Organic Cyclic Compound Binding
Biological Process
Autophagosome Assembly
Ubiquitin-dependent Protein Catabolic Process
Macroautophagy
Regulation Of Macroautophagy
Ubiquitin-dependent ERAD Pathway
Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Ubiquitination
Response To Endoplasmic Reticulum Stress
Aggrephagy
Cellular Response To Hypoxia
Autophagosome Maturation
Negative Regulation Of Store-operated Calcium Channel Activity
Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process
G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Mating Behavior
Circadian Rhythm
Pathways
Cargo recognition for clathrin-mediated endocytosis
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
Drugs
Ramelteon
Melatonin
Resveratrol
Agomelatine
Tasimelteon
Diseases
GWAS
Metabolite levels (
23823483
)
Refractive error (
32231278
)
Depressive symptoms measurement (somatic complaints domain) (
26997408
)
Job-related exhaustion in shift workers (
28364478
)
Obesity (
21552555
)
Interacting Genes
233 interacting genes:
ABCC2
ACOT7
ADRM1
AGPAT5
AGR2
AGR3
ANOS1
APOC2
APOC4
APP
ASCL1
ATXN3
BAG6
BPIFA1
C1QA
C1QTNF2
C1QTNF4
CALU
CCL3
CCL7
CD47
CD99
CD99L2
CDIP1
CDSN
CHGB
CHRNA3
CHRNA4
CHRNB4
CLCN2
COL10A1
COL1A2
COL9A2
COLGALT2
COMTD1
COPS4
CSN3
CSTF2
CSTF2T
CTAG1A
CTAG1B
CTAG2
CYB5R1
DAZAP2
DEFA6
DEFB115
DESI1
DEXI
DMKN
DNAJB2
DOLK
ECM1
EFEMP2
EP300
EPS15
ERP27
ERP29
ETNK1
F8
FAM163B
FAM189A2
FAM86B3P
FAS
FBXO25
FCGR2A
FGF7
FKBP2
FN1
FOLR3
FZD7
GABRA1
GABRA2
GABRA3
GABRA6
GABRB1
GABRB2
GABRB3
GABRD
GAL
GHRL
GIT2
GKAP1
GPR162
GPX3
GRM2
GUCA2A
GUCA2B
GYPB
HERC3
HES1
HGS
HK2
HSD17B12
HSPA13
IER3IP1
IGFBP6
IGL
IGLC1
IGLV2-14
IL6ST
IRF1-AS1
IST1
ITPRIPL1
JPH4
JSRP1
KLHL42
LAIR2
LAMB1
LCN2
LHX4
LITAF
LNPEP
MANBAL
MAP3K1
MCM7
MDK
MESD
MICOS10-NBL1
MIEF1
MIEF2
MLLT6
MTNR1A
MTOR
MYDGF
NAXD
NBL1
NDE1
NDOR1
NEDD8
NGLY1
NLGN3
NME3
NPPA
NPY
NT5C3A
NUP58
NXF1
OST4
P4HB
PARVA
PBXIP1
PCDH18
PCDHA4
PIAS2
PIK3IP1
PLAAT1
PLAAT2
PLAAT3
PNMA1
PPIB
PPIC
PRAP1
PRB1
PRPF40A
PRR4
PSEN1
PSEN2
PSMD4
PSMD6
PSORS1C2
PTN
RAI2
RARA
RASSF5
RIC8A
RNF144B
RNF208
RNF4
RPN1
RPS27A
RSRC2
RTL8A
RTL8B
RTL8C
SCG2
SCG5
SCMH1
SERPINE1
SERPINI2
SEZ6L
SIL1
SLC16A3
SLC29A2
SLPI
SMAD9
SMIM19
SMIM2
SMR3B
SMURF1
SOD3
SPAG8
SPARC
SRGN
STAM2
STMN3
SYNJ2BP
TARDBP
TFF1
TICAM1
TLR4
TMCO6
TMEM258
TMEM31
TMEM37
TMEM67
TMUB2
TNFRSF1A
TNFRSF1B
TREX1
TRIM23
TRIM32
TXNDC12
UBA52
UBB
UBC
UBE2I
UBE2V1
UBE3A
UBQLN2
UBQLN4
UBXN1
UBXN4
UBXN7
VWC2
WBP2
WFDC12
XPO4
ZBTB8B
ZFAND2B
ZG16
ZG16B
ZMYM5
ZNF343
159 interacting genes:
ABHD14B
ACTB
ACTN1
AMOTL2
ANKRD12
ARHGAP28
ASAP3
ASCL1
ATIC
ATP5MC3
BAG6
BAZ1A
BAZ1B
C10orf90
CALR
CAND1
CANX
CCDC167
CD99
CHD4
CIAO2B
CIT
CLASP1
CMIP
CNP
COG1
COL9A2
COMT
COX11
CTNNA1
CTPS2
CUL3
CUL7
CYP27C1
CYSRT1
DDHD2
DDX52
DPM1
ECE1
ECE2
EEF1G
EMC7
EMD
ENO2
EPS15
EXOC1
F8A1
FAM241B
FDXR
FLNA
FN1
FSTL1
GALNS
GAPDH
GATAD2B
GBA2
GEMIN2
GFPT2
GNA11
GNA13
GNAI1
GNAI2
GNAI3
GNB1
GNB4
GPR50
H2AC6
HDAC10
HIVEP2
HMGN2
HMOX2
HNRNPA0
HNRNPH1
HSPA5
IPO9
IRS4
ITPR3
KLHL12
KLHL20
KLHL5
KPNB1
KRTAP1-3
LAPTM4A
LIPE
LPP
LRP3
LRRC59
MAMLD1
MCC
MESD
MMP2
MMS19
MPDZ
MTNR1B
MYO9A
NAP1L1
NAP1L4
NAP1L5
NASP
PAXIP1
PCDHB10
PDIA6
PEX14
PGRMC1
PKD1L2
PPP2R3C
PRELID1
PSMD2
PSME4
PTPN13
PTPRD
PTX3
RAB10
RAC1
RACK1
RAP1A
RBM39
RGS12
RNF2
RNF41
RPL3
RTRAF
SLC2A3
SLC30A1
SLC6A3
SLIT1
SNAPIN
SOX11
SRI
STXBP1
SUCLA2
SURF4
SVEP1
TLN1
TM9SF1
TMEM14A
TMEM230
TMEM33
TMX2
TPP2
TRIP12
TUBB
TVP23B
UBA1
UBAP2L
UBQLN1
UBR4
USP28
USP32
USP34
VAPB
VARS1
WAPL
WASHC4
YWHAB
YWHAZ
ZC3H11A
ZDHHC16
ZNF460
Entrez ID
29979
4543
HPRD ID
05440
02812
Ensembl ID
ENSG00000135018
ENSG00000168412
Uniprot IDs
A0A024R258
Q9UMX0
P48039
PDB IDs
2JY5
2JY6
2KLC
6ME2
6ME3
6ME4
6ME5
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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