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MTNR1A and PGRMC1
Data Source:
BioGRID
(pull down, affinity chromatography technology)
HPRD
(in vivo)
MTNR1A
PGRMC1
Description
melatonin receptor 1A
progesterone receptor membrane component 1
Image
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Receptor Complex
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Plasma Membrane
Integral Component Of Plasma Membrane
Endomembrane System
Membrane
Smooth Endoplasmic Reticulum Membrane
Specific Granule Membrane
Neuron Projection
Neuronal Cell Body
Cell Body
Synapse
Molecular Function
G Protein-coupled Receptor Activity
Protein Binding
Melatonin Receptor Activity
Hormone Binding
Organic Cyclic Compound Binding
Amyloid-beta Binding
Steroid Binding
Protein Binding
Heme Binding
Protein Homodimerization Activity
Metal Ion Binding
Biological Process
G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Mating Behavior
Circadian Rhythm
Heme Biosynthetic Process
Neutrophil Degranulation
Pathways
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
Neutrophil degranulation
Drugs
Ramelteon
Melatonin
Resveratrol
Agomelatine
Tasimelteon
Dextromethorphan
Nortriptyline
Sertraline
Diseases
GWAS
Depressive symptoms measurement (somatic complaints domain) (
26997408
)
Job-related exhaustion in shift workers (
28364478
)
Obesity (
21552555
)
Interacting Genes
159 interacting genes:
ABHD14B
ACTB
ACTN1
AMOTL2
ANKRD12
ARHGAP28
ASAP3
ASCL1
ATIC
ATP5MC3
BAG6
BAZ1A
BAZ1B
C10orf90
CALR
CAND1
CANX
CCDC167
CD99
CHD4
CIAO2B
CIT
CLASP1
CMIP
CNP
COG1
COL9A2
COMT
COX11
CTNNA1
CTPS2
CUL3
CUL7
CYP27C1
CYSRT1
DDHD2
DDX52
DPM1
ECE1
ECE2
EEF1G
EMC7
EMD
ENO2
EPS15
EXOC1
F8A1
FAM241B
FDXR
FLNA
FN1
FSTL1
GALNS
GAPDH
GATAD2B
GBA2
GEMIN2
GFPT2
GNA11
GNA13
GNAI1
GNAI2
GNAI3
GNB1
GNB4
GPR50
H2AC6
HDAC10
HIVEP2
HMGN2
HMOX2
HNRNPA0
HNRNPH1
HSPA5
IPO9
IRS4
ITPR3
KLHL12
KLHL20
KLHL5
KPNB1
KRTAP1-3
LAPTM4A
LIPE
LPP
LRP3
LRRC59
MAMLD1
MCC
MESD
MMP2
MMS19
MPDZ
MTNR1B
MYO9A
NAP1L1
NAP1L4
NAP1L5
NASP
PAXIP1
PCDHB10
PDIA6
PEX14
PGRMC1
PKD1L2
PPP2R3C
PRELID1
PSMD2
PSME4
PTPN13
PTPRD
PTX3
RAB10
RAC1
RACK1
RAP1A
RBM39
RGS12
RNF2
RNF41
RPL3
RTRAF
SLC2A3
SLC30A1
SLC6A3
SLIT1
SNAPIN
SOX11
SRI
STXBP1
SUCLA2
SURF4
SVEP1
TLN1
TM9SF1
TMEM14A
TMEM230
TMEM33
TMX2
TPP2
TRIP12
TUBB
TVP23B
UBA1
UBAP2L
UBQLN1
UBR4
USP28
USP32
USP34
VAPB
VARS1
WAPL
WASHC4
YWHAB
YWHAZ
ZC3H11A
ZDHHC16
ZNF460
20 interacting genes:
BIK
CAMLG
CCDC134
CENPU
CIAO1
CREB3L1
DEFB124
EVI2B
GET3
GLP1R
GOLM1
KASH5
KCNE5
MTNR1A
PAM16
PGRMC2
SCAP
SGTB
TMEM213
ZNF71
Entrez ID
4543
10857
HPRD ID
02812
02338
Ensembl ID
ENSG00000168412
ENSG00000101856
Uniprot IDs
P48039
O00264
Q6IB11
PDB IDs
6ME2
6ME3
6ME4
6ME5
4X8Y
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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