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USP21 and MPP1
Data Source:
BioGRID
(two hybrid)
USP21
MPP1
Description
ubiquitin specific peptidase 21
membrane palmitoylated protein 1
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Plasma Membrane
Membrane
Cortical Cytoskeleton
Stereocilium
Centriolar Satellite
Molecular Function
Transcription Coactivator Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Cysteine-type Peptidase Activity
NEDD8-specific Protease Activity
Metal Ion Binding
Guanylate Kinase Activity
Protein Binding
Biological Process
Ubiquitin-dependent Protein Catabolic Process
Histone Deubiquitination
Protein Deubiquitination
Protein Phosphopantetheinylation
Neuron Projection Development
Positive Regulation Of Transcription, DNA-templated
Signal Transduction
GMP Metabolic Process
GDP Metabolic Process
Regulation Of Neutrophil Chemotaxis
Pathways
TNFR1-induced proapoptotic signaling
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
Ub-specific processing proteases
Drugs
Diseases
GWAS
Hematology traits (
23263863
)
Mean corpuscular volume (
23263863
)
Red blood cell traits (
23446634
)
Interacting Genes
59 interacting genes:
ADAMTSL4
ATXN3
AURKA
BAP1
BRCA2
CBL
CBLC
CPSF6
DTX3
EFEMP2
ESPL1
EXOSC10
FOXM1
H2AC18
HOXC10
ISG15
JOSD1
KCTD9
KRT40
LRSAM1
MAPK3
MPP1
NANOG
OTUB1
OTUB2
PCGF6
RBCK1
RNF144A
RNF185
SENP3
SENP8
SLF1
STAMBP
SYNE1
TP53
TRAF6
TRIM23
TRIM5
TRIM54
TRIM63
TRIM8
TRIM9
UBC
UBE2S
UCHL1
UCHL3
USP14
USP15
USP2
USP20
USP28
USP33
USP4
USP51
USP7
USP8
WDR47
YOD1
ZNF350
43 interacting genes:
ABCC4
ACER1
ACER2
AGPAT3
AMOTL2
AP2M1
APH1A
ATP5F1C
ATRAID
BHLHB9
DERL2
DGAT2L6
DNPEP
ERBIN
GADD45A
GSK3B
GYPC
HNRNPD
INCA1
KLHL12
MAP3K20
MEOX2
NR1H2
OPTN
PAQR8
PRIMPOL
RPRM
RPS6KA1
RPS6KA6
SGSM2
SLC35E1
SMN1
SRSF10
STK3
STUB1
SYNGR3
TK1
TMEM239
TRIM55
TRIM63
USP21
UXT
ZNF639
Entrez ID
27005
4354
HPRD ID
05291
02370
Ensembl ID
ENSG00000143258
ENSG00000130830
Uniprot IDs
Q9UK80
B4E325
Q00013
PDB IDs
2Y5B
3I3T
3MTN
2EJY
2EV8
3NEY
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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