SPART and ZFYVE9

Data Source:
HPRD (two hybrid)

		SPART	ZFYVE9
Description		spartin	zinc finger FYVE-type containing 9
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GO Annotations	Cellular Component	Cytoplasm Mitochondrial Outer Membrane Lipid Droplet Cytosol Plasma Membrane Midbody Synapse	Early Endosome Cytosol Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Protein Binding 1-phosphatidylinositol Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Abscission Negative Regulation Of BMP Signaling Pathway Lipid Droplet Organization Negative Regulation Of Collateral Sprouting In Absence Of Injury Neuromuscular Process Cell Division Regulation Of Mitochondrial Membrane Potential Adipose Tissue Development	Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway Endosomal Transport
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS
Interacting Genes		22 interacting genes: APP APPL1 DESI2 EPN2 EPS15 GPR35 ITCH MAP3K1 OTUB2 OTUD7B OTULIN PLIN3 PRKAR1A RABGEF1 SMURF1 SMURF2 TUBA1A UBAC1 USP5 WWP2 YOD1 ZFYVE9	38 interacting genes: ANKLE2 BAG6 BMP4 CHD6 CLTC CTNNB1 DAZAP2 EIF4G1 ERBIN ETS2 FHL2 JUP LRP12 NIT1 NUP155 PML PPP1CA PPP1CB PPP1CC PPP2R1A RBBP6 RHOT2 RNF11 RNPEP SCYL2 SMAD2 SMAD3 SPART ST7 SUMF2 SUPT5H SVEP1 TENT5A TGFBR1 TGFBR2 UBC UBXN11 ZMYND8
Entrez ID		23111	9372
HPRD ID		06170	04782
Ensembl ID		ENSG00000133104	ENSG00000157077
Uniprot IDs		A0A024RDV9 Q8N0X7	O95405
PDB IDs		2DL1 4U7I	1DEV 1MK2 4BKW 5MJY
Enriched GO Terms of Interacting Partners?
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