ZFYVE9 and ANKLE2

Data Source:
BioGRID (two hybrid)

		ZFYVE9	ANKLE2
Description		zinc finger FYVE-type containing 9	ankyrin repeat and LEM domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Early Endosome Cytosol Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Protein Domain Specific Binding Metal Ion Binding	Protein Binding Protein Phosphatase Regulator Activity Protein Phosphatase 2A Binding
	Biological Process	Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway Endosomal Transport	Mitotic Nuclear Envelope Reassembly Central Nervous System Development Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Phosphorylation Negative Regulation Of Apoptotic Process Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Catalytic Activity Cell Division
Pathways			Initiation of Nuclear Envelope (NE) Reformation
Drugs
Diseases
GWAS			Adult body size ( 32376654) Immune response to smallpox vaccine (IL-6) ( 22542470) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Refractive error ( 32231278)
Interacting Genes		38 interacting genes: ANKLE2 BAG6 BMP4 CHD6 CLTC CTNNB1 DAZAP2 EIF4G1 ERBIN ETS2 FHL2 JUP LRP12 NIT1 NUP155 PML PPP1CA PPP1CB PPP1CC PPP2R1A RBBP6 RHOT2 RNF11 RNPEP SCYL2 SMAD2 SMAD3 SPART ST7 SUMF2 SUPT5H SVEP1 TENT5A TGFBR1 TGFBR2 UBC UBXN11 ZMYND8	3 interacting genes: MAPK13 ZFYVE9 ZNF512B
Entrez ID		9372	23141
HPRD ID		04782	19309
Ensembl ID		ENSG00000157077	ENSG00000176915
Uniprot IDs		O95405	Q86XL3
PDB IDs		1DEV 1MK2 4BKW 5MJY
Enriched GO Terms of Interacting Partners?
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