SPART and DESI2

		SPART	DESI2
Description		spartin	desumoylating isopeptidase 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrial Outer Membrane Lipid Droplet Cytosol Plasma Membrane Midbody Synapse	Cytoplasm
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Lys63-specific Deubiquitinase Activity Ubiquitinyl Hydrolase Activity Lys48-specific Deubiquitinase Activity
	Biological Process	Abscission Negative Regulation Of BMP Signaling Pathway Lipid Droplet Organization Negative Regulation Of Collateral Sprouting In Absence Of Injury Neuromuscular Process Cell Division Regulation Of Mitochondrial Membrane Potential Adipose Tissue Development	Protein Deubiquitination Protein Phosphopantetheinylation Protein K63-linked Deubiquitination Protein Modification By Small Protein Removal Protein K48-linked Deubiquitination
Pathways
Drugs
Diseases		Hereditary spastic paraplegia (SPG)
GWAS
Interacting Genes		22 interacting genes: APP APPL1 DESI2 EPN2 EPS15 GPR35 ITCH MAP3K1 OTUB2 OTUD7B OTULIN PLIN3 PRKAR1A RABGEF1 SMURF1 SMURF2 TUBA1A UBAC1 USP5 WWP2 YOD1 ZFYVE9	11 interacting genes: ARFIP1 BNIP2 COQ8A MYG1 NFU1 PBX3 PLIN2 SEMA3G SH3GLB1 SPART THAP7
Entrez ID		23111	51029
HPRD ID		06170	15153
Ensembl ID		ENSG00000133104	ENSG00000121644
Uniprot IDs		A0A024RDV9 Q8N0X7	A0A024R5P6 A0A024R5P9 Q9BSY9
PDB IDs		2DL1 4U7I
Enriched GO Terms of Interacting Partners?
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