ZFYVE9 and LRP12

Data Source:
HPRD (in vivo, two hybrid)

		ZFYVE9	LRP12
Description		zinc finger FYVE-type containing 9	LDL receptor related protein 12
Image			No pdb structure
GO Annotations	Cellular Component	Early Endosome Cytosol Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle	Integral Component Of Plasma Membrane Clathrin-coated Pit Integral Component Of Membrane
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Protein Domain Specific Binding Metal Ion Binding	Low-density Lipoprotein Particle Receptor Activity Protein Binding
	Biological Process	Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway Endosomal Transport	Neuron Migration Endocytosis Signal Transduction Neuron Projection Development Regulation Of Growth
Pathways			Retinoid metabolism and transport
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Glaucoma (primary open-angle) ( 22570617) HOMA-B (corrected for HOMA-IR) ( 30369944) Impulsivity (attentional) ( 30718321) Irritable mood ( 29500382) Periodontitis (DPAL) ( 24024966) Systolic blood pressure ( 28739976) Vascular endothelial growth factor levels ( 21757650)
Interacting Genes		38 interacting genes: ANKLE2 BAG6 BMP4 CHD6 CLTC CTNNB1 DAZAP2 EIF4G1 ERBIN ETS2 FHL2 JUP LRP12 NIT1 NUP155 PML PPP1CA PPP1CB PPP1CC PPP2R1A RBBP6 RHOT2 RNF11 RNPEP SCYL2 SMAD2 SMAD3 SPART ST7 SUMF2 SUPT5H SVEP1 TENT5A TGFBR1 TGFBR2 UBC UBXN11 ZMYND8	6 interacting genes: ACTN2 MYOT NMRK2 RACK1 SNAPIN ZFYVE9
Entrez ID		9372	29967
HPRD ID		04782	17447
Ensembl ID		ENSG00000157077	ENSG00000147650
Uniprot IDs		O95405	Q59H02 Q9Y561
PDB IDs		1DEV 1MK2 4BKW 5MJY
Enriched GO Terms of Interacting Partners?
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