ZFYVE9 and RHOT2

Data Source:
HPRD (two hybrid)

		ZFYVE9	RHOT2
Description		zinc finger FYVE-type containing 9	ras homolog family member T2
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GO Annotations	Cellular Component	Early Endosome Cytosol Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle	Mitochondrion Cytosol Plasma Membrane Membrane Integral Component Of Mitochondrial Outer Membrane
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Protein Domain Specific Binding Metal Ion Binding	GTPase Activity Calcium Ion Binding Protein Binding GTP Binding
	Biological Process	Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway Endosomal Transport	Mitochondrion Organization Regulation Of Mitochondrion Organization Cellular Homeostasis Mitochondrion Transport Along Microtubule Regulation Of Small GTPase Mediated Signal Transduction Mitochondrial Outer Membrane Permeabilization
Pathways			Rho GTPase cycle
Drugs
Diseases
GWAS			Body mass index ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Red blood cell traits ( 23446634)
Interacting Genes		38 interacting genes: ANKLE2 BAG6 BMP4 CHD6 CLTC CTNNB1 DAZAP2 EIF4G1 ERBIN ETS2 FHL2 JUP LRP12 NIT1 NUP155 PML PPP1CA PPP1CB PPP1CC PPP2R1A RBBP6 RHOT2 RNF11 RNPEP SCYL2 SMAD2 SMAD3 SPART ST7 SUMF2 SUPT5H SVEP1 TENT5A TGFBR1 TGFBR2 UBC UBXN11 ZMYND8	5 interacting genes: PRKN SAR1A TMEM14B TMEM86B ZFYVE9
Entrez ID		9372	89941
HPRD ID		04782	15248
Ensembl ID		ENSG00000157077	ENSG00000140983
Uniprot IDs		O95405	Q8IXI1
PDB IDs		1DEV 1MK2 4BKW 5MJY	5KUT
Enriched GO Terms of Interacting Partners?
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