ZFYVE9 and RNF11

Data Source:
HPRD (two hybrid)

		ZFYVE9	RNF11
Description		zinc finger FYVE-type containing 9	ring finger protein 11
Image			No pdb structure
GO Annotations	Cellular Component	Early Endosome Cytosol Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle	Ubiquitin Ligase Complex Nucleus Early Endosome Recycling Endosome Extracellular Exosome
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Protein Domain Specific Binding Metal Ion Binding	DNA Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway Endosomal Transport	Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination
Pathways
Drugs
Diseases
GWAS			Atrial fibrillation ( 29290336) Male-pattern baldness ( 28196072) QRS duration ( 21076409)
Interacting Genes		38 interacting genes: ANKLE2 BAG6 BMP4 CHD6 CLTC CTNNB1 DAZAP2 EIF4G1 ERBIN ETS2 FHL2 JUP LRP12 NIT1 NUP155 PML PPP1CA PPP1CB PPP1CC PPP2R1A RBBP6 RHOT2 RNF11 RNPEP SCYL2 SMAD2 SMAD3 SPART ST7 SUMF2 SUPT5H SVEP1 TENT5A TGFBR1 TGFBR2 UBC UBXN11 ZMYND8	68 interacting genes: AKT1 ANKRD13A ANKRD28 APP ASCC2 AUP1 CALCOCO2 CBLB CCDC127 DCUN1D1 EPN1 EPN2 EPN3 EPS15 ERCC6 FANCL GGA1 GGA2 GGA3 HERC1 HERC2 HUWE1 IKBKG ITCH MYO6 NEDD4 NEDD4L OPTN PDCD6IP POLI PTPRC QARS1 RABGEF1 RIPK1 RNF168 RNF216 RPS27A SDCBP SMURF1 SMURF2 SNRNP70 SPRTN STAM2 STAMBP TAX1BP1 TNFAIP3 TNIP1 TOM1L2 UBA52 UBAC1 UBB UBC UBE2D1 UBE2D2 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBQLN2 UBQLN4 USP5 WWP1 WWP2 ZFYVE16 ZFYVE9 ZNF350
Entrez ID		9372	26994
HPRD ID		04782	09955
Ensembl ID		ENSG00000157077	ENSG00000123091
Uniprot IDs		O95405	Q9Y3C5
PDB IDs		1DEV 1MK2 4BKW 5MJY
Enriched GO Terms of Interacting Partners?
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