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ZFYVE9 and JUP
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
ZFYVE9
JUP
Description
zinc finger FYVE-type containing 9
junction plakoglobin
Image
GO Annotations
Cellular Component
Early Endosome
Cytosol
Early Endosome Membrane
Protein-containing Complex
Intracellular Membrane-bounded Organelle
Cornified Envelope
Extracellular Region
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Intermediate Filament
Plasma Membrane
Cell-cell Junction
Adherens Junction
Zonula Adherens
Fascia Adherens
Focal Adhesion
Cytoplasmic Side Of Plasma Membrane
Intercalated Disc
Actin Cytoskeleton
Apicolateral Plasma Membrane
Lateral Plasma Membrane
Catenin Complex
Z Disc
Hemidesmosome
Desmosome
Protein-DNA Complex
Specific Granule Lumen
Extracellular Exosome
Gamma-catenin-TCF7L2 Complex
Ficolin-1-rich Granule Lumen
Molecular Function
Protein Binding
1-phosphatidylinositol Binding
Protein Domain Specific Binding
Metal Ion Binding
Transcription Coactivator Activity
Structural Molecule Activity
Protein Binding
Protein Kinase Binding
Protein Phosphatase Binding
Nuclear Hormone Receptor Binding
Protein Homodimerization Activity
Protein-containing Complex Binding
Alpha-catenin Binding
Cadherin Binding
Cell Adhesion Molecule Binding
Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication
Cytoskeletal Protein-membrane Anchor Activity
Biological Process
Endocytosis
Transforming Growth Factor Beta Receptor Signaling Pathway
Endosomal Transport
Positive Regulation Of Cell-matrix Adhesion
Desmosome Assembly
Cell Migration
Keratinization
Adherens Junction Organization
Regulation Of Cell Population Proliferation
Positive Regulation Of Protein Import Into Nucleus
Neutrophil Degranulation
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Angiogenesis
Positive Regulation Of Transcription By RNA Polymerase II
Detection Of Mechanical Stimulus
Positive Regulation Of DNA-binding Transcription Factor Activity
Cornification
Endothelial Cell-cell Adhesion
Cellular Response To Indole-3-methanol
Protein Localization To Plasma Membrane
Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication
Regulation Of Heart Rate By Cardiac Conduction
Positive Regulation Of Canonical Wnt Signaling Pathway
Cell-cell Adhesion
Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Pathways
Adherens junctions interactions
VEGFR2 mediated vascular permeability
Neutrophil degranulation
Keratinization
Formation of the cornified envelope
Drugs
Zinc
Zinc acetate
Diseases
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Naxos disease and Carvajal syndrome
GWAS
Heel bone mineral density (
30598549
28869591
)
Interacting Genes
38 interacting genes:
ANKLE2
BAG6
BMP4
CHD6
CLTC
CTNNB1
DAZAP2
EIF4G1
ERBIN
ETS2
FHL2
JUP
LRP12
NIT1
NUP155
PML
PPP1CA
PPP1CB
PPP1CC
PPP2R1A
RBBP6
RHOT2
RNF11
RNPEP
SCYL2
SMAD2
SMAD3
SPART
ST7
SUMF2
SUPT5H
SVEP1
TENT5A
TGFBR1
TGFBR2
UBC
UBXN11
ZMYND8
52 interacting genes:
APC
ARHGDIA
AXIN1
BIRC2
BRCA1
BTRC
CCDC130
CDH1
CDH10
CDH15
CDH2
CDH5
CTNNA1
CTNNA3
CTNNBIP1
CTNND1
DDX6
DSC1
DSC2
DSC3
DSG1
DSG2
DSG3
DSP
EGFR
ERBB2
ERBB3
FER
FHL2
FYN
MUC1
NFATC4
NFKBIE
NTAQ1
PECAM1
PKD1
PKP2
PKP3
PRR35
PSEN1
PTEN
PTPN14
PTPRF
PTPRJ
PTPRK
RIBC2
RSPH14
SRC
TBP
TCF4
TCF7L2
ZFYVE9
Entrez ID
9372
3728
HPRD ID
04782
01414
Ensembl ID
ENSG00000157077
ENSG00000173801
Uniprot IDs
O95405
A0A0S2Z487
P14923
PDB IDs
1DEV
1MK2
4BKW
5MJY
3IFQ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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