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IRAK3 and CDCA5
Data Source:
BioGRID
(two hybrid)
IRAK3
CDCA5
Description
interleukin 1 receptor associated kinase 3
cell division cycle associated 5
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Chromosome, Centromeric Region
Chromatin
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Cytosol
Molecular Function
Magnesium Ion Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Chromatin Binding
Protein Binding
Protein-containing Complex Binding
Biological Process
Negative Regulation Of Cytokine-mediated Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Protein Phosphorylation
Response To Virus
Positive Regulation Of Macrophage Tolerance Induction
Negative Regulation Of Macrophage Cytokine Production
Cytokine-mediated Signaling Pathway
Negative Regulation Of NF-kappaB Transcription Factor Activity
Response To Peptidoglycan
Response To Lipopolysaccharide
Negative Regulation Of Interleukin-12 Production
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of Toll-like Receptor Signaling Pathway
Intracellular Signal Transduction
Negative Regulation Of Protein Catabolic Process
Negative Regulation Of Protein-containing Complex Disassembly
Regulation Of Protein-containing Complex Disassembly
Response To Exogenous DsRNA
Negative Regulation Of MAP Kinase Activity
Negative Regulation Of Innate Immune Response
Protein Autophosphorylation
Positive Regulation Of NF-kappaB Transcription Factor Activity
Interleukin-1-mediated Signaling Pathway
Response To Interleukin-1
Mitotic Cell Cycle
Double-strand Break Repair
Mitotic Sister Chromatid Cohesion
Mitotic Chromosome Condensation
Mitotic Metaphase Plate Congression
Positive Regulation Of Exit From Mitosis
Cell Division
Regulation Of Cohesin Loading
Pathways
MyD88:MAL(TIRAP) cascade initiated on plasma membrane
Interleukin-1 signaling
Separation of Sister Chromatids
Establishment of Sister Chromatid Cohesion
Resolution of Sister Chromatid Cohesion
Drugs
Fostamatinib
Diseases
GWAS
Smooth-surface caries (
24556642
)
White blood cell count (basophil) (
29403010
)
Interacting Genes
17 interacting genes:
ADH1B
ATP6V0B
CD14
CDCA5
COPB1
ECM1
FOLR1
HOXB7
IRAK1
IRAK2
LDB1
MYD88
NONO
NSA2
NTRK3
TICAM2
TRAF6
9 interacting genes:
CDK1
IRAK3
KDM1A
NAA10
NAA11
RPAIN
SENP2
TTLL3
XRCC6
Entrez ID
11213
113130
HPRD ID
05123
13016
Ensembl ID
ENSG00000090376
ENSG00000146670
Uniprot IDs
Q9Y616
A0A024R5D6
Q96FF9
PDB IDs
5UKE
6RUU
6ZIW
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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