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SEC23A and PIAS2
Data Source:
BioGRID
(two hybrid)
SEC23A
PIAS2
Description
SEC23 homolog A, COPII coat complex component
protein inhibitor of activated STAT 2
Image
GO Annotations
Cellular Component
Golgi Membrane
Endoplasmic Reticulum Membrane
Cytosol
ER To Golgi Transport Vesicle Membrane
Extrinsic Component Of Membrane
COPII Vesicle Coat
Perinuclear Region Of Cytoplasm
Endoplasmic Reticulum Exit Site
Nucleus
Nucleoplasm
PML Body
Nuclear Speck
Molecular Function
GTPase Activator Activity
Protein Binding
Zinc Ion Binding
RNA Polymerase II Transcription Factor Binding
DNA Binding
Transcription Coregulator Activity
Protein Binding
Transcription Factor Binding
Zinc Ion Binding
SUMO Transferase Activity
Ubiquitin Protein Ligase Binding
SUMO Ligase Activity
Biological Process
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Intracellular Protein Transport
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Positive Regulation Of GTPase Activity
COPII Vesicle Coating
Protein Localization To Plasma Membrane
COPII-coated Vesicle Cargo Loading
Regulation Of Transcription By RNA Polymerase II
Protein Sumoylation
Negative Regulation Of Androgen Receptor Signaling Pathway
Pathways
Regulation of cholesterol biosynthesis by SREBP (SREBF)
COPII-mediated vesicle transport
MHC class II antigen presentation
Cargo concentration in the ER
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
Cranio-lenticulo-sutural dysplasia (CLSD); Boyadjiev-Jabs syndrome
GWAS
Metabolite levels (
23823483
)
Vitamin D levels (
29343764
)
Fruit consumption (
32066663
)
Interacting Genes
35 interacting genes:
BNIP3
CADPS
CDK16
CDK18
CLEC17A
DCTN1
DNM2
DTX2
ERGIC3
ERLIN1
FASLG
FATE1
GJA8
GLRA2
HOMEZ
MFF
MIA2
MIA3
MINAR1
NDRG1
PIAS2
RNF19B
SDCBP2
SEC16A
SEC23B
SEC23IP
SEC24B
SEC24C
SEC24D
SF1
SLC7A1
SUCLA2
TMEM45B
TNFSF14
WBP11
125 interacting genes:
ACY3
ADA
AKT1
AR
ATF2
C1QA
C5orf24
CBS
CBSL
CCHCR1
CCNDBP1
CDCA8
CGGBP1
CHMP4B
CLDN2
CREB1
CREBBP
CTBP1
DDX39B
DES
DEUP1
DMC1
DNMT3A
EDC3
ELK1
ESR1
ESR2
EXOSC8
FAM118B
FKBP6
FLI1
GFAP
GLUL
GOLGA2
GRHL2
GRM8
GTF2I
GTF2IRD1
HDAC3
HMBOX1
HMG20A
HMG20B
HMGXB4
HNRNPCL1
HNRNPUL1
HOMER1
HOOK1
HUWE1
IKZF1
IMPDH1
JUN
KIFC3
LCE1E
LCE2C
LMNA
LMNB1
MAPK8
MAPKAPK2
MBD1
MITF
MLX
MSX2
MX1
MX2
NAV2
NME7
NR3C1
PAICS
PARK7
PAXIP1
PGR
PHC1
PIAS1
PIAS4
PLAG1
PLAGL1
PML
PRKAB2
PRKRA
PRPH
RFX2
RUFY1
RUNX1T1
SEC23A
SIAH1
SIAH2
SMAD3
SMAD4
SNAI2
SNIP1
SOX5
SPATC1L
SPINDOC
SREBF2
STAT4
SUMO1
SUMO1P1
SUMO2
SUMO3
SYN3
TH
TICAM2
TP53
TRAF2
TRAF3
TRAF5
TRIM23
TRIM27
TRIM50
TRIM55
TRIM63
TSR2
TXLNA
UBASH3B
UBE2I
UBE2L3
UBQLN1
ZBED1
ZBTB16
ZBTB8A
ZC3H10
ZFP42
ZNF319
ZNF451
ZNRD2
Entrez ID
10484
9063
HPRD ID
06714
06944
Ensembl ID
ENSG00000100934
ENSG00000078043
Uniprot IDs
Q15436
A0A024RC49
O75928
Q2TA77
PDB IDs
2NUP
2NUT
2YRC
2YRD
3EFO
3EG9
3EGD
3EGX
5KYN
5KYU
5KYW
5KYX
5KYY
5VNE
5VNF
5VNG
5VNH
5VNI
5VNJ
5VNK
5VNL
5VNM
5VNN
5VNO
2ASQ
4FO9
Enriched GO Terms of Interacting Partners
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