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SEC23A and GJA8
Data Source:
BioGRID
(two hybrid)
SEC23A
GJA8
Description
SEC23 homolog A, COPII coat complex component
gap junction protein alpha 8
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Endoplasmic Reticulum Membrane
Cytosol
ER To Golgi Transport Vesicle Membrane
Extrinsic Component Of Membrane
COPII Vesicle Coat
Perinuclear Region Of Cytoplasm
Endoplasmic Reticulum Exit Site
Integral Component Of Plasma Membrane
Connexin Complex
Molecular Function
GTPase Activator Activity
Protein Binding
Zinc Ion Binding
Gap Junction Channel Activity
Protein Binding
Identical Protein Binding
Biological Process
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Intracellular Protein Transport
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Positive Regulation Of GTPase Activity
COPII Vesicle Coating
Protein Localization To Plasma Membrane
COPII-coated Vesicle Cargo Loading
Lens Development In Camera-type Eye
Cell-cell Signaling
Transmembrane Transport
Gap Junction-mediated Intercellular Transport
Pathways
Regulation of cholesterol biosynthesis by SREBP (SREBF)
COPII-mediated vesicle transport
MHC class II antigen presentation
Cargo concentration in the ER
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Gap junction assembly
Drugs
Diseases
Cranio-lenticulo-sutural dysplasia (CLSD); Boyadjiev-Jabs syndrome
GWAS
Metabolite levels (
23823483
)
Vitamin D levels (
29343764
)
Retinopathy x type 2 diabetes interaction (
32541925
)
Interacting Genes
35 interacting genes:
BNIP3
CADPS
CDK16
CDK18
CLEC17A
DCTN1
DNM2
DTX2
ERGIC3
ERLIN1
FASLG
FATE1
GJA8
GLRA2
HOMEZ
MFF
MIA2
MIA3
MINAR1
NDRG1
PIAS2
RNF19B
SDCBP2
SEC16A
SEC23B
SEC23IP
SEC24B
SEC24C
SEC24D
SF1
SLC7A1
SUCLA2
TMEM45B
TNFSF14
WBP11
121 interacting genes:
ABL1
ACKR2
APOA2
APOD
APOL3
AQP4
ARL6IP6
ATP6V0B
C1GALT1
C2CD2L
C3orf52
CCDC167
CCL4
CD53
CIAO2A
CLDN19
CLDN4
CLEC1A
CLN6
COX20
CTXN3
CXCL16
CYBC1
CYP4F2
DEFB121
DOLK
ERMP1
FDFT1
FXYD6
GIMAP1
GIMAP5
GJB2
GPR108
GPR151
GPR61
GUCA2A
IGFBP5
INSIG2
ITGAM
KIR2DL3
LAPTM4B
LAT
LEPROTL1
LHFPL5
MAL
MALL
MARCHF2
MFSD11
MFSD6
MGST2
MIP
MS4A13
ORMDL2
OTOP2
P2RY13
PGAP2
PLN
PMP22
PNLIPRP1
PRAF2
PROKR2
PTPRN
QRFPR
REEP6
RNF152
RUSF1
RXFP4
S1PR5
SCARF1
SEC22B
SEC22C
SEC23A
SFTPC
SLC13A2
SLC13A5
SLC16A12
SLC16A13
SLC16A3
SLC30A3
SLC35A4
SLC35F1
SLC35F6
SLC38A4
SLC38A7
SLC39A2
SLC39A7
SLC39A9
SLC52A1
SLC66A1
SLC66A2
SLC8A3
SMCO4
SMIM1
STX1B
STX8
THSD7B
TJP1
TMBIM6
TMEM100
TMEM107
TMEM121
TMEM128
TMEM147
TMEM182
TMEM239
TMEM242
TMEM243
TMEM42
TMEM45A
TMEM60
TMEM65
TMEM72
TMEM86B
TSPAN33
TWSG1
UBXN8
UNC93A
UPK1B
VAMP5
YIF1A
YIPF6
Entrez ID
10484
2703
HPRD ID
06714
02939
Ensembl ID
ENSG00000100934
ENSG00000121634
Uniprot IDs
Q15436
P48165
X5D7G1
PDB IDs
2NUP
2NUT
2YRC
2YRD
3EFO
3EG9
3EGD
3EGX
5KYN
5KYU
5KYW
5KYX
5KYY
5VNE
5VNF
5VNG
5VNH
5VNI
5VNJ
5VNK
5VNL
5VNM
5VNN
5VNO
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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