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SEC23A and CDK16
Data Source:
HPRD
(in vivo, two hybrid, in vitro)
SEC23A
CDK16
Description
SEC23 homolog A, COPII coat complex component
cyclin dependent kinase 16
Image
GO Annotations
Cellular Component
Golgi Membrane
Endoplasmic Reticulum Membrane
Cytosol
ER To Golgi Transport Vesicle Membrane
Extrinsic Component Of Membrane
COPII Vesicle Coat
Perinuclear Region Of Cytoplasm
Endoplasmic Reticulum Exit Site
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Synaptic Vesicle
Microtubule Cytoskeleton
Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane
Neuron Projection
Molecular Function
GTPase Activator Activity
Protein Binding
Zinc Ion Binding
Protein Serine/threonine Kinase Activity
Cyclin-dependent Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Biological Process
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Intracellular Protein Transport
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Positive Regulation Of GTPase Activity
COPII Vesicle Coating
Protein Localization To Plasma Membrane
COPII-coated Vesicle Cargo Loading
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Protein Phosphorylation
Exocytosis
Spermatogenesis
Growth Hormone Secretion
Neuron Projection Development
Regulation Of Cell Cycle
Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Pathways
Regulation of cholesterol biosynthesis by SREBP (SREBF)
COPII-mediated vesicle transport
MHC class II antigen presentation
Cargo concentration in the ER
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
(2Z,3E)-2,3'-biindole-2',3(1H,1'H)-dione 3-{O-[(3R)-3,4-dihydroxybutyl]oxime}
Fostamatinib
Diseases
Cranio-lenticulo-sutural dysplasia (CLSD); Boyadjiev-Jabs syndrome
GWAS
Metabolite levels (
23823483
)
Vitamin D levels (
29343764
)
Interacting Genes
35 interacting genes:
BNIP3
CADPS
CDK16
CDK18
CLEC17A
DCTN1
DNM2
DTX2
ERGIC3
ERLIN1
FASLG
FATE1
GJA8
GLRA2
HOMEZ
MFF
MIA2
MIA3
MINAR1
NDRG1
PIAS2
RNF19B
SDCBP2
SEC16A
SEC23B
SEC23IP
SEC24B
SEC24C
SEC24D
SF1
SLC7A1
SUCLA2
TMEM45B
TNFSF14
WBP11
18 interacting genes:
APP
APPBP2
ATRIP
BAG6
CCND3
CDK5
CDK5R1
PJA1
PRKACA
S100A10
SEC23A
SIRPA
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
ZBTB14
Entrez ID
10484
5127
HPRD ID
06714
02409
Ensembl ID
ENSG00000100934
ENSG00000102225
Uniprot IDs
Q15436
A0A024R183
A0A140VK97
Q00536
Q9BRL4
PDB IDs
2NUP
2NUT
2YRC
2YRD
3EFO
3EG9
3EGD
3EGX
5KYN
5KYU
5KYW
5KYX
5KYY
5VNE
5VNF
5VNG
5VNH
5VNI
5VNJ
5VNK
5VNL
5VNM
5VNN
5VNO
3MTL
5G6V
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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