SEC23A and SDCBP2

Data Source:
BioGRID (two hybrid)

		SEC23A	SDCBP2
Description		SEC23 homolog A, COPII coat complex component	syndecan binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Extrinsic Component Of Membrane COPII Vesicle Coat Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site	Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Nuclear Speck Extracellular Exosome
	Molecular Function	GTPase Activator Activity Protein Binding Zinc Ion Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Protein C-terminus Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of GTPase Activity COPII Vesicle Coating Protein Localization To Plasma Membrane COPII-coated Vesicle Cargo Loading	Nervous System Development Cell Population Proliferation Intracellular Signal Transduction Intracellular Transport
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases		Cranio-lenticulo-sutural dysplasia (CLSD); Boyadjiev-Jabs syndrome
GWAS		Metabolite levels ( 23823483) Vitamin D levels ( 29343764)	Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483)
Interacting Genes		35 interacting genes: BNIP3 CADPS CDK16 CDK18 CLEC17A DCTN1 DNM2 DTX2 ERGIC3 ERLIN1 FASLG FATE1 GJA8 GLRA2 HOMEZ MFF MIA2 MIA3 MINAR1 NDRG1 PIAS2 RNF19B SDCBP2 SEC16A SEC23B SEC23IP SEC24B SEC24C SEC24D SF1 SLC7A1 SUCLA2 TMEM45B TNFSF14 WBP11	65 interacting genes: ADAP1 AKAP17A AP1M1 ARF4 BEND7 C1orf35 CHCHD1 CRCT1 CRY2 CT45A1 CT45A10 CT45A3 CT45A5 CTH DMC1 DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 HSBP1 LGALS14 LGALS2 LYAR MED4 NFASC NFU1 NKAPD1 NOP56 NPM2 NRXN1 NUF2 PAFAH1B3 PHC1 PRM2 PRPF38A PRPF40A PRR13 PTMS RNF111 RNPS1 RPL22 RPL22L1 RPL41 SDCBP SEC23A SREK1IP1 SYT17 TCP11L1 TDO2 THAP6 TIFA TM4SF1 TNNT1 TNP1 TRAF1 VAX1 VPS25 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2
Entrez ID		10484	27111
HPRD ID		06714	18032
Ensembl ID		ENSG00000100934	ENSG00000125775
Uniprot IDs		Q15436	Q9H190
PDB IDs		2NUP 2NUT 2YRC 2YRD 3EFO 3EG9 3EGD 3EGX 5KYN 5KYU 5KYW 5KYX 5KYY 5VNE 5VNF 5VNG 5VNH 5VNI 5VNJ 5VNK 5VNL 5VNM 5VNN 5VNO
Enriched GO Terms of Interacting Partners?
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