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GJA8 and STX1B
Data Source:
BioGRID
(two hybrid)
GJA8
STX1B
Description
gap junction protein alpha 8
syntaxin 1B
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Plasma Membrane
Connexin Complex
Nucleus
Microtubule Organizing Center
Spindle
Cytosol
Plasma Membrane
Synaptic Vesicle
Endomembrane System
Membrane
Integral Component Of Membrane
Axon
SNARE Complex
Neuromuscular Junction
Presynaptic Active Zone Membrane
Molecular Function
Gap Junction Channel Activity
Protein Binding
Identical Protein Binding
SNARE Binding
Signaling Receptor Binding
SNAP Receptor Activity
Protein Binding
Protein Kinase Binding
Protein Domain Specific Binding
Biological Process
Lens Development In Camera-type Eye
Cell-cell Signaling
Transmembrane Transport
Gap Junction-mediated Intercellular Transport
Positive Regulation Of Neurotransmitter Secretion
Intracellular Protein Transport
Exocytosis
Vesicle Docking Involved In Exocytosis
Vesicle Fusion
Regulation Of Gene Expression
Regulation Of Synaptic Vesicle Priming
Negative Regulation Of Neuron Projection Development
Synaptic Vesicle Docking
Regulation Of Exocytosis
Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
Vesicle Docking
Calcium Ion-regulated Exocytosis Of Neurotransmitter
Regulation Of Synaptic Activity
Spontaneous Neurotransmitter Secretion
Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane
Negative Regulation Of Synaptic Vesicle Recycling
Positive Regulation Of Spontaneous Neurotransmitter Secretion
Negative Regulation Of Macropinocytosis
Positive Regulation Of Excitatory Postsynaptic Potential
Pathways
Gap junction assembly
Toxicity of botulinum toxin type C (botC)
LGI-ADAM interactions
Drugs
Diseases
GWAS
Retinopathy x type 2 diabetes interaction (
32541925
)
Adult body size (
32376654
)
Body mass index (
31453325
)
Body mass index variance (
31453325
)
Dementia with Lewy bodies (
29263008
)
Hip circumference (
31453325
)
Hip circumference variance (
31453325
)
Juvenile myoclonic epilepsy (
30531953
)
Low density lipoprotein cholesterol levels (
32154731
)
Parkinson's disease (
25064009
32201043
)
Psoriasis (
25574825
)
Response to metformin (IC50) (
28173075
)
Waist circumference (
31453325
)
Waist circumference variance (
31453325
)
Interacting Genes
121 interacting genes:
ABL1
ACKR2
APOA2
APOD
APOL3
AQP4
ARL6IP6
ATP6V0B
C1GALT1
C2CD2L
C3orf52
CCDC167
CCL4
CD53
CIAO2A
CLDN19
CLDN4
CLEC1A
CLN6
COX20
CTXN3
CXCL16
CYBC1
CYP4F2
DEFB121
DOLK
ERMP1
FDFT1
FXYD6
GIMAP1
GIMAP5
GJB2
GPR108
GPR151
GPR61
GUCA2A
IGFBP5
INSIG2
ITGAM
KIR2DL3
LAPTM4B
LAT
LEPROTL1
LHFPL5
MAL
MALL
MARCHF2
MFSD11
MFSD6
MGST2
MIP
MS4A13
ORMDL2
OTOP2
P2RY13
PGAP2
PLN
PMP22
PNLIPRP1
PRAF2
PROKR2
PTPRN
QRFPR
REEP6
RNF152
RUSF1
RXFP4
S1PR5
SCARF1
SEC22B
SEC22C
SEC23A
SFTPC
SLC13A2
SLC13A5
SLC16A12
SLC16A13
SLC16A3
SLC30A3
SLC35A4
SLC35F1
SLC35F6
SLC38A4
SLC38A7
SLC39A2
SLC39A7
SLC39A9
SLC52A1
SLC66A1
SLC66A2
SLC8A3
SMCO4
SMIM1
STX1B
STX8
THSD7B
TJP1
TMBIM6
TMEM100
TMEM107
TMEM121
TMEM128
TMEM147
TMEM182
TMEM239
TMEM242
TMEM243
TMEM42
TMEM45A
TMEM60
TMEM65
TMEM72
TMEM86B
TSPAN33
TWSG1
UBXN8
UNC93A
UPK1B
VAMP5
YIF1A
YIPF6
29 interacting genes:
ABHD16A
ACBD5
AQP6
BET1
EBP
ERGIC3
FAM161B
FAM209A
FAM81A
FBXO28
FGA
GJA8
GPR152
KCNN4
MMGT1
NAPB
SNAP23
SNAP29
SNAP47
STX2
STX4
STXBP1
TMEM167B
TXLNA
UBE2I
UNC13B
VAMP1
VAMP2
VAMP5
Entrez ID
2703
112755
HPRD ID
02939
18126
Ensembl ID
ENSG00000121634
ENSG00000099365
Uniprot IDs
P48165
X5D7G1
P61266
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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