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GJA8 and ORMDL2
Data Source:
BioGRID
(two hybrid)
GJA8
ORMDL2
Description
gap junction protein alpha 8
ORMDL sphingolipid biosynthesis regulator 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Integral Component Of Plasma Membrane
Connexin Complex
Endoplasmic Reticulum
Integral Component Of Membrane
SPOTS Complex
Molecular Function
Gap Junction Channel Activity
Protein Binding
Identical Protein Binding
Protein Binding
Biological Process
Lens Development In Camera-type Eye
Cell-cell Signaling
Transmembrane Transport
Gap Junction-mediated Intercellular Transport
Ceramide Metabolic Process
Cellular Sphingolipid Homeostasis
Negative Regulation Of Ceramide Biosynthetic Process
Pathways
Gap junction assembly
Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS
Retinopathy x type 2 diabetes interaction (
32541925
)
Refractive error (
32231278
)
Interacting Genes
121 interacting genes:
ABL1
ACKR2
APOA2
APOD
APOL3
AQP4
ARL6IP6
ATP6V0B
C1GALT1
C2CD2L
C3orf52
CCDC167
CCL4
CD53
CIAO2A
CLDN19
CLDN4
CLEC1A
CLN6
COX20
CTXN3
CXCL16
CYBC1
CYP4F2
DEFB121
DOLK
ERMP1
FDFT1
FXYD6
GIMAP1
GIMAP5
GJB2
GPR108
GPR151
GPR61
GUCA2A
IGFBP5
INSIG2
ITGAM
KIR2DL3
LAPTM4B
LAT
LEPROTL1
LHFPL5
MAL
MALL
MARCHF2
MFSD11
MFSD6
MGST2
MIP
MS4A13
ORMDL2
OTOP2
P2RY13
PGAP2
PLN
PMP22
PNLIPRP1
PRAF2
PROKR2
PTPRN
QRFPR
REEP6
RNF152
RUSF1
RXFP4
S1PR5
SCARF1
SEC22B
SEC22C
SEC23A
SFTPC
SLC13A2
SLC13A5
SLC16A12
SLC16A13
SLC16A3
SLC30A3
SLC35A4
SLC35F1
SLC35F6
SLC38A4
SLC38A7
SLC39A2
SLC39A7
SLC39A9
SLC52A1
SLC66A1
SLC66A2
SLC8A3
SMCO4
SMIM1
STX1B
STX8
THSD7B
TJP1
TMBIM6
TMEM100
TMEM107
TMEM121
TMEM128
TMEM147
TMEM182
TMEM239
TMEM242
TMEM243
TMEM42
TMEM45A
TMEM60
TMEM65
TMEM72
TMEM86B
TSPAN33
TWSG1
UBXN8
UNC93A
UPK1B
VAMP5
YIF1A
YIPF6
21 interacting genes:
AQP6
CD79A
CREB3L1
CYB561
CYB5R3
DAPK1
EBP
ELOVL4
FAM210B
FCER1G
GJA8
KCNJ6
MMGT1
RETREG3
SCN3B
SLC10A1
TMEM120A
TMEM31
TMEM86B
TMX2
ZDHHC15
Entrez ID
2703
29095
HPRD ID
02939
17802
Ensembl ID
ENSG00000121634
ENSG00000123353
Uniprot IDs
P48165
X5D7G1
Q53FV1
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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