FAM110A and TRIM69

Data Source:
BioGRID (two hybrid, two hybrid)

		FAM110A	TRIM69
Description		family with sequence similarity 110 member A	tripartite motif containing 69
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Microtubule Organizing Center	Nucleus Cytoplasm Cytosol Nuclear Speck
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process		Protein Polyubiquitination Apoptotic Process Protein Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Prostate cancer ( 31562322)	Estimated glomerular filtration rate in non-diabetics ( 31451708)
Interacting Genes		52 interacting genes: AGR2 BICD2 CCNDBP1 CDR2 COG4 COG6 CSNK1E CTDSP1 CTNNA3 DYNC1I1 EFEMP1 EFEMP2 FHL3 FSD2 GOLGA2 GOLGA6L9 HOOK2 HSF2BP KRT15 KRT27 KRT31 KRT34 KRT37 KRT38 KRT39 KRTAP10-8 LDOC1 LIX1 MEIS3 MIF4GD MKRN3 MTUS2 MYOG PFDN5 PNMA1 PYGM RASSF10 RASSF3 RCN1 RINT1 ROPN1 STX11 TCF4 TRIM23 TRIM27 TRIM54 TRIM69 TSC1 TSG101 USHBP1 VPS52 ZSCAN4	53 interacting genes: AIFM2 APP ASNS ATP5MC1 BEX2 BIN3 C4orf45 CDSN DVL1 ETFDH FAM110A FAM161A FAM90A1 FKBP1B GEM HAUS1 HGS IYD KLHL38 KRT17 LARP1B LYSMD1 MAGEA4 MAJIN MED20 MID2 NEK8 NTAQ1 PML POLR3K PPP1R18 RECK RINT1 RSPH14 SF1 SF3A3 SKIL STMN3 SYCE2 SYNE4 TNNT2 TRIM44 TRIM54 TRIM55 TRIM63 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N WASHC1 WWOX ZNF483
Entrez ID		83541	140691
HPRD ID		12775	11518
Ensembl ID		ENSG00000125898	ENSG00000185880
Uniprot IDs		Q9BQ89	H0YL66 Q86WT6
PDB IDs			4NQJ 6YXE
Enriched GO Terms of Interacting Partners?
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