TRIM69 and ETFDH

Data Source:
BioGRID (two hybrid)

		TRIM69	ETFDH
Description		tripartite motif containing 69	electron transfer flavoprotein dehydrogenase
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Nuclear Speck	Mitochondrial Matrix Integral Component Of Mitochondrial Inner Membrane Mitochondrial Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Electron-transferring-flavoprotein Dehydrogenase Activity Protein Binding Electron Transfer Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Metal Ions, Flavin As Acceptor Metal Ion Binding Quinone Binding Ubiquinone Binding Flavin Adenine Dinucleotide Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Protein Polyubiquitination Apoptotic Process Protein Ubiquitination	Response To Oxidative Stress Electron Transport Chain Respiratory Electron Transport Chain Fatty Acid Beta-oxidation Using Acyl-CoA Dehydrogenase
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Respiratory electron transport
Drugs			Metformin 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
Diseases			Glutaric acidemia; Glutaric acidemia, type I (GA1); Glutaric acidemia, type II (GA2); Multiple acyl coenzyme A dehydrogenase deficiency
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708)	Acylcarnitine levels ( 26068415) Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Blood protein levels ( 28240269) Metabolic traits ( 21886157) Metabolite levels ( 31628463 20037589) Serum metabolite levels ( 23093944)
Interacting Genes		53 interacting genes: AIFM2 APP ASNS ATP5MC1 BEX2 BIN3 C4orf45 CDSN DVL1 ETFDH FAM110A FAM161A FAM90A1 FKBP1B GEM HAUS1 HGS IYD KLHL38 KRT17 LARP1B LYSMD1 MAGEA4 MAJIN MED20 MID2 NEK8 NTAQ1 PML POLR3K PPP1R18 RECK RINT1 RSPH14 SF1 SF3A3 SKIL STMN3 SYCE2 SYNE4 TNNT2 TRIM44 TRIM54 TRIM55 TRIM63 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N WASHC1 WWOX ZNF483	8 interacting genes: GSC2 HSD17B10 KRTAP11-1 KRTAP13-2 MYH7B OTX1 TRIM69 ZNF581
Entrez ID		140691	2110
HPRD ID		11518	01978
Ensembl ID		ENSG00000185880	ENSG00000171503
Uniprot IDs		H0YL66 Q86WT6	B4DEQ0 Q16134
PDB IDs		4NQJ 6YXE
Enriched GO Terms of Interacting Partners?
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