TRIM69 and BIN3

Data Source:
BioGRID (two hybrid)

		TRIM69	BIN3
Description		tripartite motif containing 69	bridging integrator 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Nuclear Speck	Cytoplasm Actin Cytoskeleton
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Cytoskeletal Anchor Activity Lipid Binding
	Biological Process	Protein Polyubiquitination Apoptotic Process Protein Ubiquitination	Division Septum Assembly Endocytosis Actin Filament Organization Protein Localization Unidimensional Cell Growth Regulation Of Lamellipodium Assembly Myoblast Migration Involved In Skeletal Muscle Regeneration Skeletal Muscle Fiber Development Actin Cortical Patch Localization Cytoskeleton-dependent Cytokinesis Plasma Membrane Tubulation
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708)	Estimated glomerular filtration rate ( 31152163) Exploratory eye movement dysfunction in schizophrenia (cognitive search score) ( 26242244) Heel bone mineral density ( 30598549) Parkinson's disease ( 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		53 interacting genes: AIFM2 APP ASNS ATP5MC1 BEX2 BIN3 C4orf45 CDSN DVL1 ETFDH FAM110A FAM161A FAM90A1 FKBP1B GEM HAUS1 HGS IYD KLHL38 KRT17 LARP1B LYSMD1 MAGEA4 MAJIN MED20 MID2 NEK8 NTAQ1 PML POLR3K PPP1R18 RECK RINT1 RSPH14 SF1 SF3A3 SKIL STMN3 SYCE2 SYNE4 TNNT2 TRIM44 TRIM54 TRIM55 TRIM63 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N WASHC1 WWOX ZNF483	9 interacting genes: ABI2 C14orf119 GINS4 NXF1 POLR1C RPRD1B TRIM69 TXLNA UBL5
Entrez ID		140691	55909
HPRD ID		11518	05904
Ensembl ID		ENSG00000185880	ENSG00000147439
Uniprot IDs		H0YL66 Q86WT6	E5RHU4 Q9NQY0
PDB IDs		4NQJ 6YXE
Enriched GO Terms of Interacting Partners?
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