TRIM69 and ZNF483

Data Source:
BioGRID (two hybrid)

		TRIM69	ZNF483
Description		tripartite motif containing 69	zinc finger protein 483
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Nuclear Speck	Nucleus
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Metal Ion Binding
	Biological Process	Protein Polyubiquitination Apoptotic Process Protein Ubiquitination	Regulation Of Transcription By RNA Polymerase II
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Generic Transcription Pathway
Drugs
Diseases
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708)	Age at voice drop ( 27182965) Apolipoprotein A1 levels ( 32203549) Height ( 31562340) Menarche (age at onset) ( 27182965 21102462 23599027 25231870) Pubertal anthropometrics ( 23449627)
Interacting Genes		53 interacting genes: AIFM2 APP ASNS ATP5MC1 BEX2 BIN3 C4orf45 CDSN DVL1 ETFDH FAM110A FAM161A FAM90A1 FKBP1B GEM HAUS1 HGS IYD KLHL38 KRT17 LARP1B LYSMD1 MAGEA4 MAJIN MED20 MID2 NEK8 NTAQ1 PML POLR3K PPP1R18 RECK RINT1 RSPH14 SF1 SF3A3 SKIL STMN3 SYCE2 SYNE4 TNNT2 TRIM44 TRIM54 TRIM55 TRIM63 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N WASHC1 WWOX ZNF483	14 interacting genes: APP CAMTA2 CRX ECPAS LBX1 MEOX2 SCAND1 TRIM69 USHBP1 ZKSCAN4 ZNF446 ZNF496 ZSCAN21 ZSCAN22
Entrez ID		140691	158399
HPRD ID		11518	18345
Ensembl ID		ENSG00000185880	ENSG00000173258
Uniprot IDs		H0YL66 Q86WT6	Q6P088 Q8TF39
PDB IDs		4NQJ 6YXE	2CTU
Enriched GO Terms of Interacting Partners?
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