TRIM69 and SYCE2

Data Source:
BioGRID (two hybrid)

		TRIM69	SYCE2
Description		tripartite motif containing 69	synaptonemal complex central element protein 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Nuclear Speck	Central Element Nucleoplasm Chromosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Protein Polyubiquitination Apoptotic Process Protein Ubiquitination	Synaptonemal Complex Assembly Cell Division
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Meiotic synapsis
Drugs
Diseases
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708)	Clozapine-induced agranulocytosis ( 25187353) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Red blood cell traits ( 23222517) Red cell distribution width ( 32888494)
Interacting Genes		53 interacting genes: AIFM2 APP ASNS ATP5MC1 BEX2 BIN3 C4orf45 CDSN DVL1 ETFDH FAM110A FAM161A FAM90A1 FKBP1B GEM HAUS1 HGS IYD KLHL38 KRT17 LARP1B LYSMD1 MAGEA4 MAJIN MED20 MID2 NEK8 NTAQ1 PML POLR3K PPP1R18 RECK RINT1 RSPH14 SF1 SF3A3 SKIL STMN3 SYCE2 SYNE4 TNNT2 TRIM44 TRIM54 TRIM55 TRIM63 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N WASHC1 WWOX ZNF483	13 interacting genes: CCDC196 CDC37 GAD2 HOMER1 IFT20 KIFC3 MED11 MED4 NAP1L5 TEX12 TRIM69 TRIML2 TSNAX
Entrez ID		140691	256126
HPRD ID		11518	19522
Ensembl ID		ENSG00000185880	ENSG00000161860
Uniprot IDs		H0YL66 Q86WT6	Q6PIF2
PDB IDs		4NQJ 6YXE	6R17
Enriched GO Terms of Interacting Partners?
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