FAM110A and HOOK2

Data Source:
BioGRID (two hybrid)

		FAM110A	HOOK2
Description		family with sequence similarity 110 member A	hook microtubule tethering protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Microtubule Organizing Center	Cytoplasm Centrosome Cytosol Microtubule HOPS Complex Intracellular Membrane-bounded Organelle FHF Complex
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding Identical Protein Binding Dynein Light Intermediate Chain Binding
	Biological Process		Endocytosis Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Early Endosome To Late Endosome Transport
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Prostate cancer ( 31562322)	High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Platelet distribution width ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		52 interacting genes: AGR2 BICD2 CCNDBP1 CDR2 COG4 COG6 CSNK1E CTDSP1 CTNNA3 DYNC1I1 EFEMP1 EFEMP2 FHL3 FSD2 GOLGA2 GOLGA6L9 HOOK2 HSF2BP KRT15 KRT27 KRT31 KRT34 KRT37 KRT38 KRT39 KRTAP10-8 LDOC1 LIX1 MEIS3 MIF4GD MKRN3 MTUS2 MYOG PFDN5 PNMA1 PYGM RASSF10 RASSF3 RCN1 RINT1 ROPN1 STX11 TCF4 TRIM23 TRIM27 TRIM54 TRIM69 TSC1 TSG101 USHBP1 VPS52 ZSCAN4	121 interacting genes: ABLIM1 AKTIP ANKRD11 ANKRD36BP1 AP1M1 APEX2 ATG5 BYSL C1orf109 CABP2 CBX8 CCDC187 CCDC198 CCDC33 CDK18 CDKN1A CEP95 CWF19L2 CYTH4 DCX DDX6 DUSP13 EIF3D ENKD1 EPS8 FAM107A FAM110A FAM161A FAM161B FAM50B FAM90A1 FGF16 FLYWCH1 GAS2L2 GEM GPKOW HAUS1 HDAC4 HOOK1 HOOK3 HOXB5 IL16 IPP IQCE ITSN2 KANSL1 KAT7 KIAA0408 KIF9 KLK15 KRT1 LENG1 LNX1 LRGUK MCM10 MCRS1 MFAP1 MORN3 MPPED2 MYLIP NEK6 OAS1 PARP11 PIMREG PKP1 PKP2 PPP1R18 PPP1R26 PRPF18 PRPF31 PRR35 PSMA1 PSMF1 RABGEF1 RALBP1 RBM41 RCOR3 RGS8 RIBC2 RITA1 RNF169 RNF6 SCNM1 SH2D4A SMARCB1 SNW1 SPATC1L SUV39H1 SYT17 SYT6 TBC1D22B TBC1D30 TCEANC TCHP TPM3 TSGA10 TSGA10IP TTC23 USP2 UTP14A UTP14C VPS16 VPS41 ZBTB47 ZC2HC1C ZC3H14 ZFP1 ZFYVE26 ZGPAT ZNF107 ZNF250 ZNF35 ZNF417 ZNF48 ZNF497 ZNF572 ZNF587 ZNF638 ZNF648 ZNF835 ZNF844
Entrez ID		83541	29911
HPRD ID		12775	09698
Ensembl ID		ENSG00000125898	ENSG00000095066
Uniprot IDs		Q9BQ89	Q96ED9
PDB IDs
Enriched GO Terms of Interacting Partners?
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