TRIM69 and RSPH14

Data Source:
BioGRID (two hybrid, two hybrid)

		TRIM69	RSPH14
Description		tripartite motif containing 69	radial spoke head 14 homolog
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Nuclear Speck	Cellular_component
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Molecular_function Protein Binding
	Biological Process	Protein Polyubiquitination Apoptotic Process Protein Ubiquitination	Biological_process
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Estimated glomerular filtration rate in non-diabetics ( 31451708)	Serum parathyroid hormone levels ( 27927781)
Interacting Genes		53 interacting genes: AIFM2 APP ASNS ATP5MC1 BEX2 BIN3 C4orf45 CDSN DVL1 ETFDH FAM110A FAM161A FAM90A1 FKBP1B GEM HAUS1 HGS IYD KLHL38 KRT17 LARP1B LYSMD1 MAGEA4 MAJIN MED20 MID2 NEK8 NTAQ1 PML POLR3K PPP1R18 RECK RINT1 RSPH14 SF1 SF3A3 SKIL STMN3 SYCE2 SYNE4 TNNT2 TRIM44 TRIM54 TRIM55 TRIM63 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N WASHC1 WWOX ZNF483	41 interacting genes: ABI2 AGAP1 ALS2CL AP1M1 AP2M1 AP3M1 BPIFA1 CCDC102B CDR2 CNTROB COG6 EPS8 FHL3 GABPB1 GOLGA2 JUP KASH5 KIFC3 KRT15 KRT31 KRT40 KRT75 KRT76 LZTS1 MNS1 PIBF1 POLR1C REL RPH3AL RSPH3 SEPTIN12 SMAD4 TCF4 TRAF2 TRIM27 TRIM50 TRIM69 TRIM7 VPS9D1 ZNF474 ZNF629
Entrez ID		140691	27156
HPRD ID		11518	16136
Ensembl ID		ENSG00000185880	ENSG00000100218
Uniprot IDs		H0YL66 Q86WT6	Q9UHP6
PDB IDs		4NQJ 6YXE
Enriched GO Terms of Interacting Partners?
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