KRT17 and TRIM69

Data Source:
BioGRID (two hybrid)

		KRT17	TRIM69
Description		keratin 17	tripartite motif containing 69
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Intermediate Filament Cytoskeleton Cell Periphery	Nucleus Cytoplasm Cytosol Nuclear Speck
	Molecular Function	Structural Molecule Activity Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Positive Regulation Of Cell Growth Hair Follicle Morphogenesis Keratinization Intermediate Filament Organization Positive Regulation Of Translation Positive Regulation Of Hair Follicle Development Cornification	Protein Polyubiquitination Apoptotic Process Protein Ubiquitination
Pathways		Keratinization Formation of the cornified envelope	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS			Estimated glomerular filtration rate in non-diabetics ( 31451708)
Interacting Genes		11 interacting genes: APC CCDC85B EGFR HRAS KDM1A KRT6A KRT7 KRT72 SNAPIN TRIM69 ZDHHC17	53 interacting genes: AIFM2 APP ASNS ATP5MC1 BEX2 BIN3 C4orf45 CDSN DVL1 ETFDH FAM110A FAM161A FAM90A1 FKBP1B GEM HAUS1 HGS IYD KLHL38 KRT17 LARP1B LYSMD1 MAGEA4 MAJIN MED20 MID2 NEK8 NTAQ1 PML POLR3K PPP1R18 RECK RINT1 RSPH14 SF1 SF3A3 SKIL STMN3 SYCE2 SYNE4 TNNT2 TRIM44 TRIM54 TRIM55 TRIM63 UBE2D1 UBE2D3 UBE2E1 UBE2H UBE2N WASHC1 WWOX ZNF483
Entrez ID		3872	140691
HPRD ID		01019	11518
Ensembl ID		ENSG00000128422	ENSG00000185880
Uniprot IDs		Q04695 Q14666	H0YL66 Q86WT6
PDB IDs			4NQJ 6YXE
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?