KRT17 and KRT6A

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KRT17	KRT6A
Description		keratin 17	keratin 6A
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Intermediate Filament Cytoskeleton Cell Periphery	Nucleus Cytosol Membrane Keratin Filament Extracellular Exosome
	Molecular Function	Structural Molecule Activity Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Positive Regulation Of Cell Growth Hair Follicle Morphogenesis Keratinization Intermediate Filament Organization Positive Regulation Of Translation Positive Regulation Of Hair Follicle Development Cornification	Negative Regulation Of Cytolysis By Symbiont Of Host Cells Morphogenesis Of An Epithelium Cytoskeleton Organization Positive Regulation Of Cell Population Proliferation Cell Differentiation Keratinization Wound Healing Defense Response To Gram-positive Bacterium Cytolysis By Host Of Symbiont Cells Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cornification Negative Regulation Of Entry Of Bacterium Into Host Cell
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope
Drugs			Zinc Zinc acetate
Diseases		Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex	Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS			Cutaneous squamous cell carcinoma ( 32041948)
Interacting Genes		11 interacting genes: APC CCDC85B EGFR HRAS KDM1A KRT6A KRT7 KRT72 SNAPIN TRIM69 ZDHHC17	38 interacting genes: BEX2 CCDC85B DSP GEM GOLGA2 HGS KDM1A KIFC3 KRT13 KRT15 KRT16 KRT17 KRT18 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT34 KRT35 KRT36 KRT38 KRT40 LMNA MTUS2 NCALD NUP62 SGTA SMARCB1 TCHP TFIP11 TRIM23 TRIM54 TSGA10 TXLNB UBQLN2 WASHC3
Entrez ID		3872	3853
HPRD ID		01019	01011
Ensembl ID		ENSG00000128422	ENSG00000205420
Uniprot IDs		Q04695 Q14666	A0A0S2Z428 P02538
PDB IDs			5KI0
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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