EFS and SORBS3

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		EFS	SORBS3
Description		embryonal Fyn-associated substrate	sorbin and SH3 domain containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane	Nucleus Cytosol Cytoskeleton Focal Adhesion
	Molecular Function	Protein Binding SH3 Domain Binding Protein Domain Specific Binding	Structural Constituent Of Cytoskeleton Protein Binding Transcription Factor Binding Vinculin Binding
	Biological Process	Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Migration Intracellular Signal Transduction Actin Filament Reorganization	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Actin Filament Organization Cell Adhesion Cell-substrate Adhesion Positive Regulation Of MAPK Cascade Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Stress Fiber Assembly
Pathways			Smooth Muscle Contraction
Drugs
Diseases
GWAS			Diastolic blood pressure ( 30224653) HIV-1 viral setpoint ( 20205591) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Parkinson's disease ( 28892059)
Interacting Genes		24 interacting genes: ABI2 APP BCAR1 BLK CRK FYN LYST NCK1 NCK2 NLGN3 NPAS2 NUP155 OSTF1 PTK2 PTK2B PTPN12 SH2D3C SORBS2 SORBS3 SRC TRAPPC6A TSSK1B UBC ZNF417	46 interacting genes: ABL1 ADAM15 ADAMTSL4 ARNT2 CBLB CPEB2 CPNE2 CPSF7 DDX17 DIP2A DLG5 DMRTB1 DVL2 EFS EIF3H FASLG FLOT1 HNRNPK HNRNPUL1 INPPL1 KIAA0408 KIAA1217 MAPK1 MAPK3 NCK1 NCKIPSD NOTCH3 PAK2 PAK5 RBMX SAFB2 SAXO1 SH2D4A SOCS7 SRCIN1 TBC1D22B TRIM23 TRIM27 TRIM41 VARS2 VPS37B VPS37C ZBED1 ZBTB25 ZBTB7B ZC4H2
Entrez ID		10278	10174
HPRD ID		09932	11535
Ensembl ID		ENSG00000100842	ENSG00000120896
Uniprot IDs		O43281	O60504
PDB IDs			2CT3 2DLM 2NWM 2YUP
Enriched GO Terms of Interacting Partners?
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