SORBS3 and TRIM41

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SORBS3	TRIM41
Description		sorbin and SH3 domain containing 3	tripartite motif containing 41
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GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Focal Adhesion	Nucleolus Cytoplasm Nuclear Body
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Transcription Factor Binding Vinculin Binding	Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Actin Filament Organization Cell Adhesion Cell-substrate Adhesion Positive Regulation Of MAPK Cascade Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Stress Fiber Assembly	Protein Ubiquitination Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide
Pathways		Smooth Muscle Contraction	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) HIV-1 viral setpoint ( 20205591) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Parkinson's disease ( 28892059)
Interacting Genes		46 interacting genes: ABL1 ADAM15 ADAMTSL4 ARNT2 CBLB CPEB2 CPNE2 CPSF7 DDX17 DIP2A DLG5 DMRTB1 DVL2 EFS EIF3H FASLG FLOT1 HNRNPK HNRNPUL1 INPPL1 KIAA0408 KIAA1217 MAPK1 MAPK3 NCK1 NCKIPSD NOTCH3 PAK2 PAK5 RBMX SAFB2 SAXO1 SH2D4A SOCS7 SRCIN1 TBC1D22B TRIM23 TRIM27 TRIM41 VARS2 VPS37B VPS37C ZBED1 ZBTB25 ZBTB7B ZC4H2	62 interacting genes: AEN AKTIP APP BRAP CEP44 CHD2 CSNK2A2 DEPTOR EHHADH FAM124A FRA10AC1 GPATCH2L IKBKG KIFC3 KRTAP10-9 MAGEH1 MEOX2 MORF4L1 MPP3 NCK2 NEDD4L NOD2 PHC2 PHF7 PRKCA PRKCB PRPF31 PUS7L RNPS1 SORBS3 SRPK2 TLE5 TOP3B TRAIP TRIM17 TRIM26 TRIM4 TRIM52 UBE2D2 UBE2I ZBTB24 ZBTB38 ZBTB48 ZBTB8A ZFP2 ZFP64 ZNF138 ZNF24 ZNF250 ZNF26 ZNF263 ZNF264 ZNF266 ZNF329 ZNF417 ZNF473 ZNF490 ZNF564 ZNF587 ZNF670 ZSCAN21 ZSCAN26
Entrez ID		10174	90933
HPRD ID		11535	15558
Ensembl ID		ENSG00000120896	ENSG00000146063
Uniprot IDs		O60504	Q8WV44
PDB IDs		2CT3 2DLM 2NWM 2YUP	2EGM
Enriched GO Terms of Interacting Partners?
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