SORBS3 and ZBTB25

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SORBS3	ZBTB25
Description		sorbin and SH3 domain containing 3	zinc finger and BTB domain containing 25
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Focal Adhesion	Nucleoplasm Cytoplasm
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Transcription Factor Binding Vinculin Binding	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Actin Filament Organization Cell Adhesion Cell-substrate Adhesion Positive Regulation Of MAPK Cascade Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Stress Fiber Assembly	Regulation Of Transcription, DNA-templated Gene Expression
Pathways		Smooth Muscle Contraction
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) HIV-1 viral setpoint ( 20205591) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Parkinson's disease ( 28892059)	Heel bone mineral density ( 30598549) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 27863252)
Interacting Genes		46 interacting genes: ABL1 ADAM15 ADAMTSL4 ARNT2 CBLB CPEB2 CPNE2 CPSF7 DDX17 DIP2A DLG5 DMRTB1 DVL2 EFS EIF3H FASLG FLOT1 HNRNPK HNRNPUL1 INPPL1 KIAA0408 KIAA1217 MAPK1 MAPK3 NCK1 NCKIPSD NOTCH3 PAK2 PAK5 RBMX SAFB2 SAXO1 SH2D4A SOCS7 SRCIN1 TBC1D22B TRIM23 TRIM27 TRIM41 VARS2 VPS37B VPS37C ZBED1 ZBTB25 ZBTB7B ZC4H2	22 interacting genes: APIP COIL CYP2J2 DDIT3 FCGR3A FHL2 HCLS1 KCTD1 KXD1 LZTS2 MAPK9 MDFI PCBD1 PNMA5 SEPHS1 SORBS3 SSX3 SUMO2 TNIP1 TRAF2 TSSK3 ZBTB1
Entrez ID		10174	7597
HPRD ID		11535	01926
Ensembl ID		ENSG00000120896	ENSG00000089775
Uniprot IDs		O60504	G3V2K3 P24278
PDB IDs		2CT3 2DLM 2NWM 2YUP
Enriched GO Terms of Interacting Partners?
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