SORBS3 and ZBED1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SORBS3	ZBED1
Description		sorbin and SH3 domain containing 3	zinc finger BED-type containing 1
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GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Focal Adhesion	Nuclear Chromatin Nucleoplasm Centrosome Nuclear Membrane
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Transcription Factor Binding Vinculin Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding SUMO Transferase Activity Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Actin Filament Organization Cell Adhesion Cell-substrate Adhesion Positive Regulation Of MAPK Cascade Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Stress Fiber Assembly	Protein Sumoylation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Smooth Muscle Contraction	SUMOylation of chromatin organization proteins
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) HIV-1 viral setpoint ( 20205591) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Parkinson's disease ( 28892059)
Interacting Genes		46 interacting genes: ABL1 ADAM15 ADAMTSL4 ARNT2 CBLB CPEB2 CPNE2 CPSF7 DDX17 DIP2A DLG5 DMRTB1 DVL2 EFS EIF3H FASLG FLOT1 HNRNPK HNRNPUL1 INPPL1 KIAA0408 KIAA1217 MAPK1 MAPK3 NCK1 NCKIPSD NOTCH3 PAK2 PAK5 RBMX SAFB2 SAXO1 SH2D4A SOCS7 SRCIN1 TBC1D22B TRIM23 TRIM27 TRIM41 VARS2 VPS37B VPS37C ZBED1 ZBTB25 ZBTB7B ZC4H2	29 interacting genes: AMOTL2 ATRX C1orf109 DGCR6 EFHC1 FABP4 FANCG GPN1 GPSM1 KDM1A KLHL40 LRRC20 MLH1 NIF3L1 NIP7 NUDT18 PIAS2 PRKAA1 PRKAR1A PSAP RENBP SORBS3 SPEF1 SSX2 SUMO2 TRAPPC2B TTR UBE2I UCHL5
Entrez ID		10174	9189
HPRD ID		11535	02170
Ensembl ID		ENSG00000120896	ENSG00000214717
Uniprot IDs		O60504	A0A024RBU4 O96006
PDB IDs		2CT3 2DLM 2NWM 2YUP	2CT5
Enriched GO Terms of Interacting Partners?
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