EFS and LYST

Number of citations of the paper that reports this interaction (PubMedID 11984006)
32

Data Source:
BioGRID (two hybrid)

		EFS	LYST
Description		embryonal Fyn-associated substrate	lysosomal trafficking regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane	Cytoplasm Microtubule Cytoskeleton
	Molecular Function	Protein Binding SH3 Domain Binding Protein Domain Specific Binding	Protein Binding
	Biological Process	Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Migration Intracellular Signal Transduction Actin Filament Reorganization	Lysosome Organization Protein Transport Leukocyte Chemotaxis Melanosome Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Mast Cell Secretory Granule Organization Natural Killer Cell Mediated Cytotoxicity Defense Response To Bacterium Defense Response To Protozoan Pigmentation Defense Response To Virus
Pathways
Drugs
Diseases			Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS			Post bronchodilator FEV1/FVC ratio ( 26634245) Systemic lupus erythematosus ( 26502338 19838195)
Interacting Genes		24 interacting genes: ABI2 APP BCAR1 BLK CRK FYN LYST NCK1 NCK2 NLGN3 NPAS2 NUP155 OSTF1 PTK2 PTK2B PTPN12 SH2D3C SORBS2 SORBS3 SRC TRAPPC6A TSSK1B UBC ZNF417	24 interacting genes: ATN1 CALM1 CELF4 CENPJ CNTROB CSNK2B DNAJC14 EFS ESRRA ESS2 HGS HNRNPM KPNB1 MED12 MRPL17 MRPS31 NCDN PCBP4 TNNI3 VTA1 YWHAB YWHAQ YWHAZ ZNF521
Entrez ID		10278	1130
HPRD ID		09932	06060
Ensembl ID		ENSG00000100842	ENSG00000143669
Uniprot IDs		O43281	Q99698
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?