EFS and SORBS2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		EFS	SORBS2
Description		embryonal Fyn-associated substrate	sorbin and SH3 domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane	Nucleus Plasma Membrane Focal Adhesion Actin Cytoskeleton Apical Plasma Membrane Z Disc Lamellipodium Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding SH3 Domain Binding Protein Domain Specific Binding	RNA Binding Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Adaptor Activity Structural Constituent Of Muscle
	Biological Process	Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Migration Intracellular Signal Transduction Actin Filament Reorganization	Actin Filament Organization Notch Signaling Pathway Biological_process Cell Growth Involved In Cardiac Muscle Cell Development
Pathways
Drugs
Diseases
GWAS			Cardiac Troponin-T levels ( 31014085) Cytokine and corticosteroid-stimulated IL-6 production ( 25896417) Cytokine-stimulated IL-6 production ( 25896417) Height ( 31562340) Short-term memory (digit-span task) ( 30741946) Uterine fibroid size (maximum volume) ( 30196971) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		24 interacting genes: ABI2 APP BCAR1 BLK CRK FYN LYST NCK1 NCK2 NLGN3 NPAS2 NUP155 OSTF1 PTK2 PTK2B PTPN12 SH2D3C SORBS2 SORBS3 SRC TRAPPC6A TSSK1B UBC ZNF417	37 interacting genes: ABL1 ABL2 ACTN1 ACTN4 ADAM15 AFDN AKT1 AKT2 ATPAF2 CBL DLGAP1 DLGAP2 DLGAP4 EFS EGFR FAT1 FLOT1 MDM2 NCK2 NR1H2 PAK1 PAK2 PALLD PKM PTK2B PTPN12 RPL9 SEMA6A SH2D4A SYNJ1 TRAF4 VCL VPS37C WAS WASF1 YWHAE YWHAZ
Entrez ID		10278	8470
HPRD ID		09932	12473
Ensembl ID		ENSG00000100842	ENSG00000154556
Uniprot IDs		O43281	B7Z3D7 B7Z997 O94875
PDB IDs			5VEI
Enriched GO Terms of Interacting Partners?
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