EFS and NUP155

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		EFS	NUP155
Description		embryonal Fyn-associated substrate	nucleoporin 155
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane	Nuclear Envelope Membrane Nuclear Membrane Host Cell Nuclear Pore Inner Ring
	Molecular Function	Protein Binding SH3 Domain Binding Protein Domain Specific Binding	Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Migration Intracellular Signal Transduction Actin Filament Reorganization	Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Regulation Of Glycolytic Process RNA Export From Nucleus MRNA Export From Nucleus TRNA Export From Nucleus Protein Import Into Nucleus Nuclear Envelope Organization Viral Process Protein Sumoylation Viral Transcription Protein Localization To Nuclear Inner Membrane Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Atrial Cardiac Muscle Cell Action Potential Regulation Of Cellular Response To Heat
Pathways			ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS
Interacting Genes		24 interacting genes: ABI2 APP BCAR1 BLK CRK FYN LYST NCK1 NCK2 NLGN3 NPAS2 NUP155 OSTF1 PTK2 PTK2B PTPN12 SH2D3C SORBS2 SORBS3 SRC TRAPPC6A TSSK1B UBC ZNF417	5 interacting genes: EFS GLE1 HDAC4 NUP98 ZFYVE9
Entrez ID		10278	9631
HPRD ID		09932	05984
Ensembl ID		ENSG00000100842	ENSG00000113569
Uniprot IDs		O43281	A0A024R071 B4DLT2 E9PF10 O75694
PDB IDs			5A9Q 5IJN 5IJO
Enriched GO Terms of Interacting Partners?
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