TRIM14 and CENPC

Data Source:
BioGRID (two hybrid)

		TRIM14	CENPC
Description		tripartite motif containing 14	centromere protein C
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrial Outer Membrane Cytosol Phagocytic Vesicle	Kinetochore Condensed Nuclear Chromosome Kinetochore Condensed Chromosome, Centromeric Region Nucleoplasm Pericentric Heterochromatin Cytosol Nuclear Body Midbody
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity	DNA Binding Protein Binding Centromeric DNA Binding Identical Protein Binding
	Biological Process	Protein Polyubiquitination Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Regulation Of Protein Localization Negative Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity	Mitotic Cell Cycle Chromosome Segregation CENP-A Containing Nucleosome Assembly Cell Division Attachment Of Mitotic Spindle Microtubules To Kinetochore Kinetochore Assembly Monopolar Spindle Attachment To Meiosis I Kinetochore
Pathways		Interferon gamma signaling	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Multiple sclerosis ( 31604244)	Adult body size ( 32376654) Adverse response to drug ( 30420678) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189)
Interacting Genes		84 interacting genes: ABCF3 ADAMTS12 ALG13 AP3M1 ATP1B1 ATP1B3 ATP2A2 ATP5PB ATP6V1H BYSL CARD9 CCDC125 CCDC57 CCDC6 CENPC CIB3 CKS1B CSPP1 EIF3G ERCC3 ETFBKMT EXOC8 FAM50B FAT1 GOLGA2 GOLGA6L9 HERC3 HEXIM2 HNRNPF IHO1 ITM2A IVNS1ABP KAT2B KIF3A KIFC3 LAMTOR1 LNX1 MAPRE3 MITD1 MNAT1 MRPL24 MYO15B NCOR1 NDUFA9 NFAT5 NPC2 PCGF6 PDIA6 PHF11 PIM2 PLCG1 POLR1C POLR2G PPP2R3C PRDM6 PRKAB2 PRPF31 PTPN21 RAB5A RAB9A RAD51D RBM33 RLF RNF125 RNF20 SLF2 SMARCB1 SMIM3 SPG21 STK38 TAX1BP1 TMEM167A TRAF2 TSGA10 UBE2B UBE2N UNK VIM WDR35 WRNIP1 ZC4H2 ZFP36L2 ZGPAT ZNF652	7 interacting genes: DAXX ELOC MAPK14 MDC1 SUMO2 TRIM14 UBTF
Entrez ID		9830	1060
HPRD ID		05948	00315
Ensembl ID		ENSG00000106785	ENSG00000145241
Uniprot IDs		A0A024R165 Q14142	Q03188
PDB IDs		6JBM	5LSJ 5LSK 6MUO 6MUP 6SE6 6SEE 6SEF
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?