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TRIM14 and ITM2A
Data Source:
BioGRID
(two hybrid)
TRIM14
ITM2A
Description
tripartite motif containing 14
integral membrane protein 2A
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Mitochondrial Outer Membrane
Cytosol
Phagocytic Vesicle
Golgi Apparatus
Plasma Membrane
Integral Component Of Membrane
Molecular Function
Transcription Coactivator Activity
Protein Binding
Zinc Ion Binding
Protein Kinase Binding
Protein Homodimerization Activity
Ubiquitin Protein Ligase Activity
Amyloid-beta Binding
Protein Binding
Biological Process
Protein Polyubiquitination
Regulation Of Gene Expression
Positive Regulation Of Autophagy
Protein Ubiquitination
Regulation Of Protein Localization
Negative Regulation Of Viral Transcription
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Positive Regulation Of Transcription, DNA-templated
Regulation Of Viral Entry Into Host Cell
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Plasma Cell Differentiation
Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process
Pathways
Interferon gamma signaling
Drugs
Diseases
GWAS
Multiple sclerosis (
31604244
)
Birth weight (
31043758
)
Graves' disease (
23612905
)
Height (
18391951
)
Nose size (
27182965
)
Thyrotoxic hypokalemic periodic paralysis and Graves disease (
31050781
)
Interacting Genes
84 interacting genes:
ABCF3
ADAMTS12
ALG13
AP3M1
ATP1B1
ATP1B3
ATP2A2
ATP5PB
ATP6V1H
BYSL
CARD9
CCDC125
CCDC57
CCDC6
CENPC
CIB3
CKS1B
CSPP1
EIF3G
ERCC3
ETFBKMT
EXOC8
FAM50B
FAT1
GOLGA2
GOLGA6L9
HERC3
HEXIM2
HNRNPF
IHO1
ITM2A
IVNS1ABP
KAT2B
KIF3A
KIFC3
LAMTOR1
LNX1
MAPRE3
MITD1
MNAT1
MRPL24
MYO15B
NCOR1
NDUFA9
NFAT5
NPC2
PCGF6
PDIA6
PHF11
PIM2
PLCG1
POLR1C
POLR2G
PPP2R3C
PRDM6
PRKAB2
PRPF31
PTPN21
RAB5A
RAB9A
RAD51D
RBM33
RLF
RNF125
RNF20
SLF2
SMARCB1
SMIM3
SPG21
STK38
TAX1BP1
TMEM167A
TRAF2
TSGA10
UBE2B
UBE2N
UNK
VIM
WDR35
WRNIP1
ZC4H2
ZFP36L2
ZGPAT
ZNF652
7 interacting genes:
CLDN7
FCGR1A
FNDC9
MEOX2
SIT1
TMED9
TRIM14
Entrez ID
9830
9452
HPRD ID
05948
02200
Ensembl ID
ENSG00000106785
ENSG00000078596
Uniprot IDs
A0A024R165
Q14142
O43736
PDB IDs
6JBM
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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