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TRIM14 and WDR35
Data Source:
BioGRID
(two hybrid)
TRIM14
WDR35
Description
tripartite motif containing 14
WD repeat domain 35
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Mitochondrial Outer Membrane
Cytosol
Phagocytic Vesicle
Centrosome
Cilium
Axoneme
Intraciliary Transport Particle A
Ciliary Basal Body
Ciliary Tip
Molecular Function
Transcription Coactivator Activity
Protein Binding
Zinc Ion Binding
Protein Kinase Binding
Protein Homodimerization Activity
Ubiquitin Protein Ligase Activity
Protein Binding
Biological Process
Protein Polyubiquitination
Regulation Of Gene Expression
Positive Regulation Of Autophagy
Protein Ubiquitination
Regulation Of Protein Localization
Negative Regulation Of Viral Transcription
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Positive Regulation Of Transcription, DNA-templated
Regulation Of Viral Entry Into Host Cell
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Response To Toxic Substance
Negative Regulation Of Gene Expression
Response To Lipopolysaccharide
Intraciliary Retrograde Transport
Intraciliary Transport Involved In Cilium Assembly
Intraciliary Transport
Positive Regulation Of Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Nitric Oxide Biosynthetic Process
Cilium Assembly
Protein Localization To Cilium
Cellular Response To Glucose Stimulus
Cellular Response To Tumor Necrosis Factor
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Liver Regeneration
Cellular Response To Paclitaxel
Cellular Response To Leukemia Inhibitory Factor
Pathways
Interferon gamma signaling
Hedgehog 'off' state
Intraflagellar transport
Drugs
Diseases
Cranioectodermal dysplasia
GWAS
Multiple sclerosis (
31604244
)
Coronary heart disease (
22751097
)
Facial morphology (
29921221
)
Neurological blood protein biomarker levels (
31320639
)
Interacting Genes
84 interacting genes:
ABCF3
ADAMTS12
ALG13
AP3M1
ATP1B1
ATP1B3
ATP2A2
ATP5PB
ATP6V1H
BYSL
CARD9
CCDC125
CCDC57
CCDC6
CENPC
CIB3
CKS1B
CSPP1
EIF3G
ERCC3
ETFBKMT
EXOC8
FAM50B
FAT1
GOLGA2
GOLGA6L9
HERC3
HEXIM2
HNRNPF
IHO1
ITM2A
IVNS1ABP
KAT2B
KIF3A
KIFC3
LAMTOR1
LNX1
MAPRE3
MITD1
MNAT1
MRPL24
MYO15B
NCOR1
NDUFA9
NFAT5
NPC2
PCGF6
PDIA6
PHF11
PIM2
PLCG1
POLR1C
POLR2G
PPP2R3C
PRDM6
PRKAB2
PRPF31
PTPN21
RAB5A
RAB9A
RAD51D
RBM33
RLF
RNF125
RNF20
SLF2
SMARCB1
SMIM3
SPG21
STK38
TAX1BP1
TMEM167A
TRAF2
TSGA10
UBE2B
UBE2N
UNK
VIM
WDR35
WRNIP1
ZC4H2
ZFP36L2
ZGPAT
ZNF652
1 interacting genes:
TRIM14
Entrez ID
9830
57539
HPRD ID
05948
15667
Ensembl ID
ENSG00000106785
ENSG00000118965
Uniprot IDs
A0A024R165
Q14142
Q9P2L0
PDB IDs
6JBM
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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