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JUP and ARHGDIA
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
JUP
ARHGDIA
Description
junction plakoglobin
Rho GDP dissociation inhibitor alpha
Image
GO Annotations
Cellular Component
Cornified Envelope
Extracellular Region
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Intermediate Filament
Plasma Membrane
Cell-cell Junction
Adherens Junction
Zonula Adherens
Fascia Adherens
Focal Adhesion
Cytoplasmic Side Of Plasma Membrane
Intercalated Disc
Actin Cytoskeleton
Apicolateral Plasma Membrane
Lateral Plasma Membrane
Catenin Complex
Z Disc
Hemidesmosome
Desmosome
Protein-DNA Complex
Specific Granule Lumen
Extracellular Exosome
Gamma-catenin-TCF7L2 Complex
Ficolin-1-rich Granule Lumen
Cytosol
Cytoskeleton
Membrane
Extracellular Exosome
Molecular Function
Transcription Coactivator Activity
Structural Molecule Activity
Protein Binding
Protein Kinase Binding
Protein Phosphatase Binding
Nuclear Hormone Receptor Binding
Protein Homodimerization Activity
Protein-containing Complex Binding
Alpha-catenin Binding
Cadherin Binding
Cell Adhesion Molecule Binding
Cell Adhesive Protein Binding Involved In Bundle Of His Cell-Purkinje Myocyte Communication
Cytoskeletal Protein-membrane Anchor Activity
Rho GDP-dissociation Inhibitor Activity
GTPase Activator Activity
Protein Binding
Biological Process
Positive Regulation Of Cell-matrix Adhesion
Desmosome Assembly
Cell Migration
Keratinization
Adherens Junction Organization
Regulation Of Cell Population Proliferation
Positive Regulation Of Protein Import Into Nucleus
Neutrophil Degranulation
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Angiogenesis
Positive Regulation Of Transcription By RNA Polymerase II
Detection Of Mechanical Stimulus
Positive Regulation Of DNA-binding Transcription Factor Activity
Cornification
Endothelial Cell-cell Adhesion
Cellular Response To Indole-3-methanol
Protein Localization To Plasma Membrane
Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication
Regulation Of Heart Rate By Cardiac Conduction
Positive Regulation Of Canonical Wnt Signaling Pathway
Cell-cell Adhesion
Regulation Of Ventricular Cardiac Muscle Cell Action Potential
Negative Regulation Of Cell Adhesion
Rho Protein Signal Transduction
Regulation Of Rho Protein Signal Transduction
Negative Regulation Of Apoptotic Process
Positive Regulation Of GTPase Activity
Negative Regulation Of Axonogenesis
Positive Regulation Of Axonogenesis
Regulation Of Small GTPase Mediated Signal Transduction
Semaphorin-plexin Signaling Pathway
Regulation Of Actin Cytoskeleton Reorganization
Pathways
Adherens junctions interactions
VEGFR2 mediated vascular permeability
Neutrophil degranulation
Keratinization
Formation of the cornified envelope
Axonal growth inhibition (RHOA activation)
Rho GTPase cycle
Axonal growth stimulation
Drugs
Zinc
Zinc acetate
Diseases
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Naxos disease and Carvajal syndrome
GWAS
Heel bone mineral density (
30598549
28869591
)
Interacting Genes
52 interacting genes:
APC
ARHGDIA
AXIN1
BIRC2
BRCA1
BTRC
CCDC130
CDH1
CDH10
CDH15
CDH2
CDH5
CTNNA1
CTNNA3
CTNNBIP1
CTNND1
DDX6
DSC1
DSC2
DSC3
DSG1
DSG2
DSG3
DSP
EGFR
ERBB2
ERBB3
FER
FHL2
FYN
MUC1
NFATC4
NFKBIE
NTAQ1
PECAM1
PKD1
PKP2
PKP3
PRR35
PSEN1
PTEN
PTPN14
PTPRF
PTPRJ
PTPRK
RIBC2
RSPH14
SRC
TBP
TCF4
TCF7L2
ZFYVE9
41 interacting genes:
ACTL6A
ADRB2
ATXN3
BAK1
CASP3
CASP7
CBX5
CDC42
CDKN1B
EP300
FEN1
HAAO
HDAC6
HERPUD1
IKBKG
JUP
KAT2B
MAPK6
NEDD4L
POT1
RAC1
RAC2
RAC3
RDX
RHOA
RHOG
RHOH
SDHC
SH3GL3
SIRT2
ST3GAL4
SUMO4
TERF1
TINF2
TRIM13
TWF2
UBE2I
UBE2L6
UBE2R2
UFM1
VAV1
Entrez ID
3728
396
HPRD ID
01414
03565
Ensembl ID
ENSG00000173801
ENSG00000141522
Uniprot IDs
A0A0S2Z487
P14923
J3QQX2
P52565
V9HWE8
PDB IDs
3IFQ
1CC0
1FSO
1FST
1FT0
1FT3
1HH4
1KMT
1QVY
1RHO
2BXW
2JHS
2JHT
2JHU
2JHV
2JHW
2JHX
2JHY
2JHZ
2JI0
2N80
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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