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ACTN3 and POU6F2
Data Source:
BioGRID
(two hybrid)
ACTN3
POU6F2
Description
actinin alpha 3
POU class 6 homeobox 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Actin Filament
Focal Adhesion
Pseudopodium
Extracellular Exosome
Chromatin
Nucleus
Molecular Function
Actin Binding
Integrin Binding
Calcium Ion Binding
Protein Binding
Structural Constituent Of Muscle
Identical Protein Binding
Ion Channel Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Biological Process
Regulation Of The Force Of Skeletal Muscle Contraction
Skeletal Muscle Atrophy
Transition Between Fast And Slow Fiber
Response To Denervation Involved In Regulation Of Muscle Adaptation
Muscle Filament Sliding
Regulation Of Apoptotic Process
Negative Regulation Of Glycolytic Process
Focal Adhesion Assembly
Positive Regulation Of Skeletal Muscle Tissue Growth
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Negative Regulation Of Oxidative Phosphorylation
Negative Regulation Of Cold-induced Thermogenesis
Regulation Of Aerobic Respiration
Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Ganglion Mother Cell Fate Determination
Central Nervous System Development
Visual Perception
Pathways
Nephrin family interactions
Striated Muscle Contraction
Drugs
Diseases
GWAS
Bipolar disorder (
21926972
)
Frontotemporal dementia with GRN mutation (
29724592
)
Adult body size (
32376654
)
Attention deficit hyperactivity disorder (inattention symptoms) (
32595297
)
Feeling hurt (
29500382
)
Glaucoma (multi-trait analysis) (
31959993
)
Hand grip strength (
29691431
)
Intraocular pressure (
29785010
31959993
30054594
)
Motion sickness (
25628336
)
Refractive error (
32231278
)
Tea consumption (
31046077
)
Interacting Genes
61 interacting genes:
ABI3
ACTN1
ACTN2
ACTN4
ADORA2A
ASB9
ATP23
BRCA1
C1orf94
C20orf85
C2CD6
CADPS
CTAG1A
CTAG1B
CTDSP1
CXCL5
DDAH2
DUX1
DUX4L9
ECM1
FAM90A1
GLIS2
HGS
HOXD12
HSF2BP
IVD
KCTD6
KRT6C
LHX3
LINC01554
LNX1
MAGEA6
MICALL2
MYOT
MYOZ1
MYPN
NDUFAB1
NEBL
NKAPD1
NRAP
ODF3B
PCCB
PKP2
PLEKHG2
POU6F2
PPP1R18
PTK6
REL
RNF111
RTP5
SNAI1
SOHLH1
SUMO1P1
SYNPO2L
TRAF1
TRAF2
TRIM29
TTN
USP2
ZNF343
ZNF426
143 interacting genes:
ACTN3
ANKRD10
ARHGEF6
ASB13
BANP
BFSP2
BHLHE40
C1orf109
C5
CCHCR1
CCNC
CCNK
CDC23
CDC37
CDKN2C
CHAF1A
CIB3
CINP
CSNK2A1
CSTF2
CTNNA3
DDX6
DTNB
DYDC1
EBF1
EIF3F
EIF4EBP1
EPHB6
FHL2
FNDC3B
FOSB
GCM2
GLIS2
GMEB2
GOLGA6L9
HGS
HIVEP1
HNF1B
HOXC5
HOXC8
HSPA4
IGFN1
IMPDH2
IQUB
IRX4
ISX
KDF1
KIF5B
KLHL11
KPNA5
KPNA6
KRTAP8-1
L3MBTL2
LARP4
LMNB2
LMO3
LNX1
LONRF1
MAGEA12
MAPK9
MEIS2
MIEN1
MLLT10
MORF4L2
MSRB3
MSX2
MYL7
MYO15B
NEUROG3
NFYC
NKX3-2
NME7
NUP62CL
OAZ3
OIP5
OPLAH
OPTN
PADI4
PARVG
PDE6H
PIBF1
PKN1
PM20D2
POLR3C
POU2F1
PPIL1
PPIP5K2
PROP1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
QRICH1
RAD23B
RBM39
RBPMS
RELA
SIX1
SMAD5
SMYD1
SORL1
SOX10
SSUH2
STAC
STRA8
TBX6
TCEA2
TENT5B
THADA
THAP1
TLX2
TLX3
TNPO2
TNXB
TP53BP1
TRIM73
TRIML2
TSC1
TSEN15
TTC19
TTC23
UBAC1
UFSP1
VAX2
VENTX
VEZF1
VPS9D1
XPOT
ZBTB24
ZBTB4
ZFHX2
ZFHX3
ZFP1
ZFP91
ZIM2
ZMYND12
ZNF148
ZNF319
ZNF34
ZNF384
ZNF410
ZNF574
Entrez ID
89
11281
HPRD ID
02148
10162
Ensembl ID
ENSG00000248746
ENSG00000106536
Uniprot IDs
A0A087WSZ2
B4DZQ2
Q08043
P78424
PDB IDs
1TJT
1WKU
3LUE
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Intersection)
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