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ACTN3 and MICALL2
Data Source:
BioGRID
(two hybrid)
ACTN3
MICALL2
Description
actinin alpha 3
MICAL like 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Actin Filament
Focal Adhesion
Pseudopodium
Extracellular Exosome
Stress Fiber
Cytosol
Plasma Membrane
Cell-cell Junction
Bicellular Tight Junction
Actin Filament Bundle
Neuron Projection
Recycling Endosome
Molecular Function
Actin Binding
Integrin Binding
Calcium Ion Binding
Protein Binding
Structural Constituent Of Muscle
Identical Protein Binding
Ion Channel Binding
Protein Binding
Filamin Binding
Small GTPase Binding
Actinin Binding
Metal Ion Binding
Actin Filament Binding
Biological Process
Regulation Of The Force Of Skeletal Muscle Contraction
Skeletal Muscle Atrophy
Transition Between Fast And Slow Fiber
Response To Denervation Involved In Regulation Of Muscle Adaptation
Muscle Filament Sliding
Regulation Of Apoptotic Process
Negative Regulation Of Glycolytic Process
Focal Adhesion Assembly
Positive Regulation Of Skeletal Muscle Tissue Growth
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Negative Regulation Of Oxidative Phosphorylation
Negative Regulation Of Cold-induced Thermogenesis
Regulation Of Aerobic Respiration
Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate
Actin Filament Polymerization
Neuron Projection Development
Actin Cytoskeleton Reorganization
Endocytic Recycling
Substrate Adhesion-dependent Cell Spreading
Bicellular Tight Junction Assembly
Positive Regulation Of Protein Targeting To Mitochondrion
Pathways
Nephrin family interactions
Striated Muscle Contraction
Drugs
Diseases
GWAS
Bipolar disorder (
21926972
)
Frontotemporal dementia with GRN mutation (
29724592
)
Blood urea nitrogen levels (
29403010
)
Creatinine levels (
29403010
)
Executive inhibition (Stroop WIT and CIT) in attention deficit hyperactivity disorder (
28416812
)
Glomerular filtration rate (
29403010
)
Hematocrit (
29403010
)
Hemoglobin (
29403010
)
Red blood cell count (
29403010
)
Resistance to antihypertensive treatment in hypertension (
31545351
)
Serum uric acid levels (
30993211
29403010
)
Zinc levels (
26025379
)
Interacting Genes
61 interacting genes:
ABI3
ACTN1
ACTN2
ACTN4
ADORA2A
ASB9
ATP23
BRCA1
C1orf94
C20orf85
C2CD6
CADPS
CTAG1A
CTAG1B
CTDSP1
CXCL5
DDAH2
DUX1
DUX4L9
ECM1
FAM90A1
GLIS2
HGS
HOXD12
HSF2BP
IVD
KCTD6
KRT6C
LHX3
LINC01554
LNX1
MAGEA6
MICALL2
MYOT
MYOZ1
MYPN
NDUFAB1
NEBL
NKAPD1
NRAP
ODF3B
PCCB
PKP2
PLEKHG2
POU6F2
PPP1R18
PTK6
REL
RNF111
RTP5
SNAI1
SOHLH1
SUMO1P1
SYNPO2L
TRAF1
TRAF2
TRIM29
TTN
USP2
ZNF343
ZNF426
6 interacting genes:
ACTN1
ACTN2
ACTN3
ACTN4
CDR2
DCDC2
Entrez ID
89
79778
HPRD ID
02148
11364
Ensembl ID
ENSG00000248746
ENSG00000164877
Uniprot IDs
A0A087WSZ2
B4DZQ2
Q08043
Q6UWK3
Q8IY33
PDB IDs
1TJT
1WKU
3LUE
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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