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ACTN3 and C2CD6
Data Source:
BioGRID
(two hybrid)
ACTN3
C2CD6
Description
actinin alpha 3
C2 calcium dependent domain containing 6
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Actin Filament
Focal Adhesion
Pseudopodium
Extracellular Exosome
Molecular Function
Actin Binding
Integrin Binding
Calcium Ion Binding
Protein Binding
Structural Constituent Of Muscle
Identical Protein Binding
Ion Channel Binding
Protein Binding
Biological Process
Regulation Of The Force Of Skeletal Muscle Contraction
Skeletal Muscle Atrophy
Transition Between Fast And Slow Fiber
Response To Denervation Involved In Regulation Of Muscle Adaptation
Muscle Filament Sliding
Regulation Of Apoptotic Process
Negative Regulation Of Glycolytic Process
Focal Adhesion Assembly
Positive Regulation Of Skeletal Muscle Tissue Growth
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Negative Regulation Of Oxidative Phosphorylation
Negative Regulation Of Cold-induced Thermogenesis
Regulation Of Aerobic Respiration
Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate
Pathways
Nephrin family interactions
Striated Muscle Contraction
Drugs
Diseases
GWAS
Bipolar disorder (
21926972
)
Frontotemporal dementia with GRN mutation (
29724592
)
Interacting Genes
61 interacting genes:
ABI3
ACTN1
ACTN2
ACTN4
ADORA2A
ASB9
ATP23
BRCA1
C1orf94
C20orf85
C2CD6
CADPS
CTAG1A
CTAG1B
CTDSP1
CXCL5
DDAH2
DUX1
DUX4L9
ECM1
FAM90A1
GLIS2
HGS
HOXD12
HSF2BP
IVD
KCTD6
KRT6C
LHX3
LINC01554
LNX1
MAGEA6
MICALL2
MYOT
MYOZ1
MYPN
NDUFAB1
NEBL
NKAPD1
NRAP
ODF3B
PCCB
PKP2
PLEKHG2
POU6F2
PPP1R18
PTK6
REL
RNF111
RTP5
SNAI1
SOHLH1
SUMO1P1
SYNPO2L
TRAF1
TRAF2
TRIM29
TTN
USP2
ZNF343
ZNF426
62 interacting genes:
ACOT11
ACTN3
ANKK1
AP2B1
BBS4
BHLHB9
BRCA1
CARD9
CCDC172
CCDC57
CCDC85B
CDR2
CHCHD3
CNOT11
CT55
DISC1
DNAJA3
FAM217B
FHL2
GOLGA2
GRAMD4
HAP1
HSF2BP
HSPB8
IKZF3
JRK
KIFC3
KRT13
KRT15
KRT31
KRT40
KRT75
LHX1
LHX3
LZTS2
MCM6
MCRS1
MEAF6
MEOX1
MIPOL1
MTUS2
NR5A1
NUTM1
PAX6
PIBF1
RNF8
SPATA2
TACC3
TCP10L
TEX11
TFIP11
TLE5
TRAF1
TRAF2
TRIM23
TRIM54
TSSK3
VAC14
VIM
VPS52
ZNF474
ZNRD2
Entrez ID
89
151254
HPRD ID
02148
08687
Ensembl ID
ENSG00000248746
ENSG00000155754
Uniprot IDs
A0A087WSZ2
B4DZQ2
Q08043
A0A140VJE2
Q53TS8
PDB IDs
1TJT
1WKU
3LUE
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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